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Neural stem cells reside in the subventricular zone (SVZ) of the adult mammalian brain. This germinal region, which continually generates new neurons destined for the olfactory bulb, is composed of… (More)
- Fiona Doetsch, Jose Manuel GarcÃa-Verdugo, Arturo Alvarez-Buylla
- The Journal of neuroscience : the official…
- 1997
The adult mammalian subventricular zone (SVZ) contains stem cells that give rise to neurons and glia. In vivo, SVZ progeny migrate 3-8 mm to the olfactory bulb, where they form neurons. We show here… (More)
- Arnold R Kriegstein, Arturo Alvarez-Buylla
- Annual review of neuroscience
- 2009
Glial cells were long considered end products of neural differentiation, specialized supportive cells with an origin very different from that of neurons. New studies have shown that some glial… (More)
- Zaman Mirzadeh, Florian T. Merkle, Mario Soriano-Navarro, Jose Manuel GarcÃa-Verdugo, Arturo Alvarez-Buylla
- Cell stem cell
- 2008
Neural stem cells (NSCs, B1 cells) are retained in the walls of the adult lateral ventricles but, unlike embryonic NSCs, are displaced from the ventricular zone (VZ) into the subventricular zone… (More)
Neural stem cells in the subventricular zone (SVZ) continue to generate new neurons in the adult brain. SVZ cells exposed to EGF in culture grow to form neurospheres that are multipotent and… (More)
- Carlos Lois, Arturo Alvarez-Buylla
- Science
- 1994
During the development of the mammalian brain, neuronal precursors migrate to their final destination from their site of birth in the ventricular and subventricular zones (VZ and SVZ, respectively).… (More)
- Florian T. Merkle, Zaman Mirzadeh, Arturo Alvarez-Buylla
- Science
- 2007
The in vivo potential of neural stem cells in the postnatal mouse brain is not known, but because they produce many different types of neurons, they must be either very versatile or very diverse. By… (More)
- Hynek Wichterle, Daniel H. Turnbull, Susana Nery, Gordon Fishell, Arturo Alvarez-Buylla
- Development
- 2001
Recent studies suggest that neurons born in the developing basal forebrain migrate long distances perpendicularly to radial glia and that many of these cells reach the developing neocortex. This form… (More)
- Leopoldo Petreanu, Arturo Alvarez-Buylla
- The Journal of neuroscience : the official…
- 2002
Young neurons born in the subventricular zone (SVZ) of adult mice migrate to the olfactory bulb (OB) where they differentiate into granule cells (GCs) and periglomerular interneurons. Using… (More)
- Bénédicte Menn, Jose Manuel GarcÃa-Verdugo, Cynthia Yaschine, Oscar Gonzalez-Perez, David H Rowitch, Arturo Alvarez-Buylla
- The Journal of neuroscience : the official…
- 2006
Glial fibrillary acidic protein (GFAP)-positive astrocytes (type B cells) in the subventricular zone (SVZ) generate large numbers of new neurons in the adult brain. SVZ stem cells can also generate… (More)