Arthur Y. M. Chen

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HIV/AIDS prevention has been a major concern for health department of every government. We propose to assess the impact of social behaviors on HIV epidemic. To do so, we build an agent-based computer simulation model to implement a sexual network with the existence of high risk population. In order to categorize the high risk population and low risk(More)
A six-year-old, neutered, female collie was presented to an oncology specialty service after developing tetraparesis and self-mutilation that progressively worsened while receiving chemotherapy for lymphoma. Neurologic examination revealed ataxia, paresis and diminished conscious proprioception in all limbs with entire spinal reflexes. Magnetic resonance(More)
BJECTIVES The CYP19 gene encodes aromatase—a key enzyme involved in the conversion of androstenedione/testosterone to estrone/estradiol. In this study, we analyzed the association between the TCT insertion (Ins)/deletion (Del) and TTTA repeat polymorphisms of CYP19 and prostate cancer (PCa). ETHODS Automated sequencer with GeneScan software was used to(More)
2546 Background: AFP464 (NSC 710464) is a lysyl derivative of aminoflavone metabolized by cytochrome P450 (CYP)1A1 and CYP1A2 (Kuffel et al, Mol Pharmacol 62:143, 2002) to reactive species that covalently bind DNA, with preclinical activity in breast, renal, and ovarian cell lines. METHODS We performed a phase I study to define the maximally tolerated(More)
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