Keratoconus is a disease of the cornea that usually begins during puberty and progressively weakens its biomechanical structure. Keratoconic eyes show a conic shape and progressive thinning, both… (More)
PURPOSE
To morphologically, biochemically, and physiologically characterize corneal cross-linking with riboflavin and UV-A light (CXL) in a newly established in vivo murine model.
METHODS
C57BL/6… (More)
PURPOSE
To establish corneal cross-linking (CXL) with riboflavin and UV-A in in the mouse cornea in vivo and to develop tools to measure the biomechanical changes observed.
METHODS
A total of 55… (More)
Purpose
We studied changes in gene transcription after corneal crosslinking (CXL) in the rabbit cornea in vivo and identified potential molecular signaling pathways.
Methods
A total of 15 corneas… (More)
PURPOSE
New corneal cross-linking (CXL) devices are capable of using higher UV-A light irradiances than used in original CXL protocols. The Bunsen-Roscoe law states that a photochemical reaction… (More)
Olivier Richoz, MD, has won the 24th Annual Richard C. Troutman, MD, DSc (Hon) Prize and $5000 award for an article published in the Journal of Refractive Surgery: “Antibacterial Efficacy of… (More)
PURPOSE
To introduce a constant-force technique for the analysis of corneal biomechanical changes induced after collagen cross-linking (CXL) that is better adapted to the natural loading in the eye… (More)
PURPOSE
To compare the currently available ultraviolet-A (UV-A) corneal cross-linking (CXL) treatment protocols for thin corneas with respect to oxygen, UV fluence, and osmotic pressure.
METHODS… (More)