Arthur Vleugels

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To explore the mechanisms underlying the shortening of the cardiac action potential in hypoxia, we studied the effect of hypoxia on the ionic currents in cat papillary and trabecular muscles using the single sucrose gap-voltage clamp technique. For potentials positive to -70 mV, hypoxia induces an increase in time-independent outward current. The changes in(More)
INTRODUCTION The aims of this study were to explore the incidence of in-hospital inappropriate empiric antibiotic use in patients with severe infection and to identify its relationship with patient outcomes. METHODS Medline (from 2004 to 2014) was systematically searched by using predefined inclusion criteria. Reference lists of retrieved articles were(More)
Adverse events are unintended patient injuries that arise from healthcare management resulting in disability, prolonged hospital stay or death. Adverse events that require intensive care admission imply a considerable financial burden to the healthcare system. The epidemiology of adverse events in Belgian hospitals has never been assessed systematically. A(More)
OBJECTIVE The objectives of this study are to determine the prevalence and preventability of adverse events requiring an unplanned higher level of care, defined as an unplanned transfer to the ICU or an in-hospital medical emergency team intervention, and to assess the type and the level of harm of each adverse event. DESIGN A three-stage retrospective(More)
501 Neer EJ (1973) The vasopressin-sensitive adenylate cyclase of the rat medulla. An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat. Effect of L-triiodothyronine on (-) [ J H]-dihydroalprenolol binding and cyclic AMP responses to (-)adrenaline in cultured heart cells. Isopro-terenol-induced cardiac(More)
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