F0F1-ATPase structural information gained from X-ray crystallography and electron microscopy has activated interest in a rotational mechanism for the F0F1-ATPase. Because of the subunit stoichiometry and the involvement of both a- and c-subunits in the mechanism of proton movement, it is argued that relative movement must occur between the subunits. Various… (More)
We present multiwavelength observations of the BL Lacertae object Markarian 501 (Mrk 501) in 1997 between April 8 and April 19. Evidence of correlated variability is seen in very high energy (VHE, E ∼ > 350 GeV) γ-ray observations taken with the Whipple Observatory γ-ray telescope, data from the Oriented Scintillation Spectrometer Experiment (OSSE) of the… (More)
Based on BACODINE network notification the Whipple Observatory gamma-ray telescope has been used to search for the delayed TeV counterpart to BATSE-detected gamma-ray bursts. In the fast slew mode, any point in the sky can be reached within two minutes of the burst notification. The search strategy, necessary because of the uncertainty in burst position and… (More)
The Crab Nebula has become established as the standard candle for TeV gamma-ray astronomy using the atmospheric Cherenkov technique. No evidence for variability has been seen. The spectrum of gamma rays from the Crab Nebula has been measured in the energy range 500 GeV to 8 TeV at the Whipple Observatory by the atmospheric Cherenkov imaging technique. Two… (More)
In this approach, small scale-length medium perturbations not modeled in the tomographic inversion might be described as random fields, characterized by particular distribution functions (e.g., normal with specified spatial covariance). Conceivably, random field parameters (scatterer density or scale length) might themselves be the targets of tomographic… (More)
Conventional multistation location estimation is not possible for small earthquakes and explosions recorded at only a single seismic station. We present a novel method of estimating epicentral distance by integrating observed travel times (Lg–Pn and Sn–Pn) measured on three-component (3C) single-station data with theoretical travel times for the same phase… (More)
The ATP synthase F1F0 is the smallest molecular motor yet studied. ATP hydrolysis drives the rotary motion of the primary stalk subunits gamma and epsilon relative to the alpha 3 beta 3 part of F1. Evidence is reviewed to show that the delta and b subunits provide a second stalk that can act as a stator to facilitate these rotational movements.
F1F0 type ATPases are made up of two parts, an F1, which contains three catalytic sites on beta subunits, and an F0 which contains the proton channel. These two domains have been visualized in electron microscopy as linked by a narrow stalk of around 45 A in length. Biochemical studies have provided clear evidence that the gamma and epsilon subunits are… (More)