F0F1-ATPase structural information gained from X-ray crystallography and electron microscopy has activated interest in a rotational mechanism for the F0F1-ATPase. Because of the subunit stoichiometry and the involvement of both a- and c-subunits in the mechanism of proton movement, it is argued that relative movement must occur between the subunits. Various… (More)
If supernova remnants (SNRs) are the site of cosmic-ray acceleration, the associated nuclear interactions should result in an observable flux of γ-rays for the nearest SNRs. Measurements of the TeV γ-ray flux from six nearby, radio-bright SNRs have been made with the Whipple Observatory imaging aiř Cerenkov telescope over the period September 1993 to June… (More)
We present multiwavelength observations of the BL Lacertae object Markarian 501 (Mrk 501) in 1997 between April 8 and April 19. Evidence of correlated variability is seen in very high energy (VHE, E ∼ > 350 GeV) γ-ray observations taken with the Whipple Observatory γ-ray telescope, data from the Oriented Scintillation Spectrometer Experiment (OSSE) of the… (More)
Based on BACODINE network notification the Whipple Observatory gamma-ray telescope has been used to search for the delayed TeV counterpart to BATSE-detected gamma-ray bursts. In the fast slew mode, any point in the sky can be reached within two minutes of the burst notification. The search strategy, necessary because of the uncertainty in burst position and… (More)
Two active galactic nuclei have been detected at TeV energies using the atmospherič Cerenkov imaging technique. The Whipple Observatory γ-ray telescope has been used to observe all the BL Lacertae objects in the northern hemisphere out to a redshift of 0.1. We report the tentative detection of VHE emission from a third BL Lac object, 1ES 2344+514. Progress… (More)
The Crab Nebula has become established as the standard candle for TeV gamma-ray astronomy using the atmospheric Cherenkov technique. No evidence for variability has been seen. The spectrum of gamma rays from the Crab Nebula has been measured in the energy range 500 GeV to 8 TeV at the Whipple Observatory by the atmospheric Cherenkov imaging technique. Two… (More)
The ATP synthase F1F0 is the smallest molecular motor yet studied. ATP hydrolysis drives the rotary motion of the primary stalk subunits gamma and epsilon relative to the alpha 3 beta 3 part of F1. Evidence is reviewed to show that the delta and b subunits provide a second stalk that can act as a stator to facilitate these rotational movements.
F1F0 type ATPases are made up of two parts, an F1, which contains three catalytic sites on beta subunits, and an F0 which contains the proton channel. These two domains have been visualized in electron microscopy as linked by a narrow stalk of around 45 A in length. Biochemical studies have provided clear evidence that the gamma and epsilon subunits are… (More)