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PURPOSE To compare the intended versus the resultant thickness of laser in situ keratomileusis (LASIK) flaps created with a new femtosecond laser and to report the 3-month postoperative refractive outcomes. SETTING Wellington Eye Clinic, Dublin, Ireland. DESIGN Retrospective consecutive case series. METHODS A consecutive series of eyes having LASIK(More)
PURPOSE The aim of this study was to investigate morphological changes, using second-harmonic (SH) optical imaging, in the corneal stroma after normal- and high-intensity collagen crosslinking in postmortem enucleated porcine eyes at controlled intraocular pressures (IOPs). METHODS Reflection-mode SH optical imaging of the stroma was realized after(More)
PURPOSE To study the effects of oxygen administered to patients having cataract surgery under local anesthesia. SETTING The Pretoria Eye Institute, Arcadia, South Africa. METHODS In this prospective study, 31 patients were randomly divided into two groups; one received oxygen inhalation during surgery and the other, air. The saturation of oxygen in(More)
PURPOSE To explore the efficacy, safety, and predictability of topography-guided laser epithelial keratomileusis (LASEK) and LASIK treatments using the ALLEGRO Oculyzer (rotating Scheimpflug image-based) as compared to the ALLEGRO Topolyzer (Placido disk-based) platform (WaveLight AG). METHODS In this retrospective, non-comparative case series, 72 eyes(More)
PURPOSE To assess the efficacy, safety, and predictability of an individualized laser in situ keratomileusis (LASIK) ablation profile based on an optical ray-tracing algorithm to treat moderate to high myopic astigmatism. SETTING Ophthalmology centers in Zurich, Switzerland; Dublin, Ireland; and, Cologne, Germany. DESIGN Multicenter clinical trail. (More)
PURPOSE To evaluate and compare the safety and efficacy of accelerated (AXL) and standard corneal cross-linking (CXL) protocols in patients with progressive keratoconus. METHODS Progressive keratoconus patients (14-40 years) received either standard-intensity CXL or high-intensity CXL (AXL). Corneas were exposed to ultraviolet-A 365 nm light for 30(More)
Corneal Cross-Linking (CXL) is an established surgical procedure for the treatment of corneal disorders such as corneal ectasia and keratoconus. This method of treatment stabilises the corneal structure and increases rigidity, reducing the requirement for corneal transplantation. Since its development, many scientific studies have been conducted to(More)
Before the discovery of corneal cross-linking (CXL), patients with keratoconus would have had to undergo corneal transplantation, or wear rigid gas permeable lenses (RGPs) that would temporarily flatten the cone, thereby improving the vision. The RGP contact lens (CL) would not however alter the corneal stability and if the keratoconus was progressive, the(More)
PURPOSE To evaluate outcomes in patients with myopia up to -12.00 diopters (D), with or without astigmatism up to 6.00 D, who underwent LASIK with the WaveLight Refractive Suite (Alcon Laboratories, Inc., Fort Worth, TX). METHODS This multicenter, prospective, single-arm study evaluated patients at baseline, on the day of surgery, and 1 day and 1, 3, and(More)