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BACKGROUND AND OBJECTIVE Sclerostin is an inhibitor of the Wnt/beta-catenin bone metabolic pathway. Increased sclerostin levels and reduced bone mineral density (BMD) have been documented in adult(More)
Higher levels of Dickkopf-1, which is an inhibitor of Wnt/β-catenin bone metabolic pathway, could be indicative of downregulated Wnt system, with possible lower osteoblast activation and higher(More)
Orthopaedic Department, Royal Hospital for Children, Glasgow,UK; Department of bone and mineral metabolism, Institute of Child Health, “Agia Sofia” Chidren’s Hospital, 11527, Athens, Greece;(More)