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Malignant ascites is a common manifestation of advanced cancers, and treatment options are limited. The trifunctional antibody catumaxomab (anti-epithelial cell-adhesion molecule x anti-CD3) represents a targeted immunotherapy for the intraperitoneal (i.p.) treatment of malignant ascites secondary to epithelial cancers. In this phase II/III trial (EudraCT(More)
OBJECTIVE. To investigate competence of general practice nurses caring for patients with mental health problems in the somatic departments. MATERIAL AND METHODS. A quantitive study on competence of general practice nurses using an anonymous questionnaire was carried out in Klaipeda secondary health care institution in January-February of 2007. The(More)
OBJECTIVE The aims of this study were to investigate the frequency of anxiety and depression in patients with benign voice disorders with respect to gender and diagnosis and to determine correlations between psychological distress and some sociodemographic factors and the Voice Handicap Index (VHI). METHODS Psychological distress was assessed for 437(More)
INTRODUCTION Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) are causing serious nosocomial infections. Tigecycline was evaluated in hospitalized patients with MRSA or VRE infection. PATIENTS AND METHODS A randomized (3:1), double-blind, multicentre, Phase 3 study compared the safety and efficacy of(More)
BACKGROUND Rectal budesonide is an effective treatment of active ulcerative proctitis or proctosigmoiditis. AIM To compare the therapeutic efficacy, tolerability and safety, and patient's preference of budesonide foam vs. budesonide enema. METHODS Patients with active ulcerative proctitis or proctosigmoiditis (clinical activity index > 4 and endoscopic(More)
The present study discusses how nurse managers' work-related empowerment has been investigated, in order to determine the level and relationships of empowerment among them. A systematic review was carried out, and a literature search was conducted with certain electronic databases for the period 1990-2009, using the main key words in various combinations.(More)
OBJECTIVE Nurse competence became a relevant topic for discussion among nurse practitioners and nurse researchers. However, the factors connected with nurse competence need deeper exploring. The aim of this study was to explore nurse competence and factors associated with it from the perspective of nurses for predicting the possible ways for upgrading the(More)
UNLABELLED The aim of this study is to describe the impact of an education intervention programme on nurses' willingness to care for HIV-positive people in Lithuania. METHODS The study utilizes a randomized controlled trial design (RCT). The total sample comprises 185 nurses working in medical, surgical and gynaecological units, and primary health care(More)
OBJECTIVE This paper reviews the current literature on intervention programs designed to improve nurses' knowledge and attitudes to human immunodeficiency virus/acquired immunodeficiency syndrome and their willingness to take care of patients with human immunodeficiency virus/acquired immunodeficiency syndrome. It also explores the impact of these(More)
Objective. To investigate the influence of high-salinity geothermal mineral water on stress and fatigue. Method. 180 seamen were randomized into three groups: geothermal (65), music (50), and control (65). The geothermal group was administered 108 g/L salinity geothermal water bath for 2 weeks five times a week. Primary outcome was effect on stress and(More)