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iv Acknowledgements I am most indebted to my wife, Nathalie, who was on my side throughout this entire adventure. She has been extremely supportive and has accepted a great deal of hardship and sacrifices to give me the necessary time to complete this project. This is her accomplishment as well! At Caltech, my foremost thanks go to my advisor, Pietro(More)
We propose a framework for simultaneous phase unwrapping and multipath interference cancellation (SPUMIC) in homo-dyne time-of-flight (ToF) cameras. Our multi-frequency acquisition framework is based on parametric modeling of the multipath interference phenomena. We use robust spectral estimation methods with low computational complexity to detect and(More)
We address the problem of autocalibration of a moving camera with unknown constant intrinsic parameters. Existing autocalibration techniques use numerical optimization algorithms whose convergence to the correct result cannot be guaranteed, in general. To address this problem, we have developed a method where an interval branch-and-bound method is employed(More)
In this paper, we present an implementation of a real-time convolver, based on Field Programmable Gate Arrays (FPGA's) to perform the convolution operations. Main characteristics of the proposed approach are the usage of external memory to implement a FIFO buffer where incoming pixels are stored and the partitioning of the convolution matrix among several(More)
Vascular endothelial growth factor (VEGF) is an important factor mediating tumour angiogenesis. VEGF mRNA is differentially expressed in bladder cancer with high expression in superficial tumours (stage pTa and pT1) contrasting with low expression in muscle invasive tumours (stage > or = pT2). To investigate mechanisms regulating VEGF expression in bladder(More)
We have designed and implemented a system for real-time detection of 2-D features on a reconfigurable computer based on Field Programmable Gate Arrays (FPGA's). We envision this device as the front-end of a system able to track image features in real-time control applications like autonomous vehicle navigation. The algorithm employed to select good features(More)
We deal with the problem of obtaining rigorous bounds to the position of 3-D points computed by stereo triangulation when both the camera matrix and the image points are affected by uncertainty. By " rigorous bounds " we mean that the true unknown 3-D points are guaranteed to lie within the given intervals. To this end we first model the calibration process(More)
Existing autocalibration techniques use numerical optimization algorithms that are prone to the problem of local minima. To address this problem, we have developed a method where an interval branch-and-bound method is employed for numerical minimization. Thanks to the properties of Interval Analysis this method is guaranteed to converge to the global(More)
The Tousled like kinase 1B (TLK1B) is critical for DNA repair and survival of cells. Upon DNA damage, Chk1 phosphorylates TLK1B at S457 leading to its transient inhibition. Once TLK1B regains its kinase activity it phosphorylates Rad9 at S328. In this work we investigated the significance of this mechanism by overexpressing mutant TLK1B in which the(More)