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OBJECTIVE To compare the long term efficacy and adverse events of dual blockade of the renin-angiotensin system with monotherapy. DESIGN Systematic review and meta-analysis. DATA SOURCES PubMed, Embase, and the Cochrane central register of controlled trials, January 1990 to August 2012. STUDY SELECTION Randomised controlled trials comparing dual(More)
  • David Melicharek, Arpit Shah, Ginnene DiStefano, Andrew J Gangemi, Andrew Orapallo, Alysia D Vrailas-Mortimer +1 other
  • 2008
Atonal is a Drosophila proneural protein required for the proper formation of the R8 photoreceptor cell, the founding photoreceptor cell in the developing retina. Proper expression and refinement of the Atonal protein is essential for the proper formation of the Drosophila adult eye. In vertebrates, expression of transcription factors orthologous to(More)
— We discuss the application of biogeography-based optimization (BBO) to invariant set approximation. BBO is a recently developed evolutionary algorithm (EA) that is motivated by biogeography, which is the study and science of the geographical migration of biological species. Invariant sets are sets in the state space of a dynamic system such that if the(More)
We present hardware testing of an evolutionary algorithm known as biogeography-based optimization (BBO) and extend it to distributed learning. BBO is an evolutionary algorithm based on the theory of biogeography, which describes how nature geographically distributes organisms. We introduce a new BBO algorithm that does not use a centralized computer, and(More)
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