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OBJECTIVE Ablative neurosurgical treatment of trigeminal neuralgia, including percutaneous radiofrequency thermocoagulation, requires cannulation of the foramen ovale. To maximize patient security and cannulation success, a frameless stereotactic system was evaluated in a phantom study, a cadaveric study, and a preliminary clinical trial. METHODS(More)
The aim of this study was to investigate the frequency and mutation status of the immunoglobulin heavy variable chain (IGHV) in a cohort of 224 patients from northwest and central region of Spain diagnosed with chronic lymphocytic leukemia (CLL), and to correlate it with cytogenetic abnormalities, overall survival (OS) and time to first treatment (TTFT).(More)
We present the current state-of-the art of computer-assisted interstitial (fractionated) brachytherapy as a "picture-book" without wanting to give an in-depth presentation of either hrachytherapy itself or of otolaryngolngic aspects of oncologic treatment. However, our results show that 3Docomputer-assisted navigation techniques can successfully be applied(More)
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