Arne M. Olsson

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OBJECTIVES To determine the efficacy and safety of fixed-dose oral sildenafil in patients with erectile dysfunction (ED) of various etiologies. METHODS In a 12-week, double-blind, randomized, placebo-controlled, fixed-dose study, 514 men (mean age 56 years) with ED were randomized to receive 25, 50, or 100 mg of sildenafil or placebo. The primary etiology(More)
The mechanism by which oral oestrogen-containing contraceptives in women and oestrogen treatment of prostatic carcinoma in men increases the risk of vascular disease is unclear. These agents decrease serum concentrations of vitamin B12, pyridoxal 5-phosphate, and folate, all of which are essential for the metabolism of the atherogenic amino acid(More)
During a 5-year period, 588 consecutive patients with nonseminomatous testicular germ cell cancer were included by 16 hospitals into the Swedish-Norwegian Testicular Cancer Project (SWENOTECA). A total of 370 (63%) had early clinical stages (CS1, CS1Mk+ and CS2A), and 345 (93%) of these patients underwent pathological staging (PS) by retroperitoneal lymph(More)
BACKGROUND Insofar as a majority of children with malignant diseases are cured, the late effects of treatment are of major importance. PROCEDURE A retrospective study was conducted of gonadal and sexual function of 77 adult male survivors of childhood malignancies treated and cured at a single center from 1970 to 1989 and followed for a median of 13(More)
Between 1981 and 1986, 279 consecutive patients with clinical stage I (CS1) nonseminomatous germ cell tumors (NSGCT) of the testis underwent pathological staging (PS) with retroperitoneal lymphadenectomy (RPLND). Patients with retroperitoneal metastases (PS2) received adjuvant chemotherapy. The median follow-up time after RPLND was 50 months (range, 30 to(More)
Congestive heart failure (CHF) is a serious disease with a poor prognosis. Diabetes is an independent risk factor for CHF, probably in part due to disturbances in myocardial metabolism. Glucagon-like peptide-1 (GLP-1) causes glucose-dependent secretion of insulin, improving glycaemic control. In turn, this may improve myocardial metabolism and myocardial(More)
Fourteen patients with priapism have been treated over the last 12 years. Two patients had a recurrence 2 and 5 years after the primary incident. Abuse of alcohol (often combined with psychotropic drugs) and the use of antihypertensive drugs were the most prominent aetiological factors. Three out of 9 patients treated conservatively and 5 out of 6 patients(More)
Ultrasound examination was performed on 51 patients with clinically pathological scrotum who all underwent surgery. Twenty patients had extratesticular disease and 31 patients had intratesticular disease. The disease was located correctly by ultrasound in all cases. It was, however, not possible to tell a malignant from a benign lesion, or a teratoma from a(More)
A new simplified electrophoretic and Western blotting technique for the study of dystrophin in muscle biopsy material is presented and compared with immune histochemistry. The method is based on separation of dystrophin in a linear SDS-PAGE pore gradient of 4-8% acrylamide in ultra-thin, horizontal gels on plastic film support followed by horizontal(More)
BACKGROUND Surgical angioplasty of the left main coronary artery (LMCA) can be performed with good results in selected patients. It restores the native antegrade blood flow in the LMCA and does not leave the patient with a graft-dependent retrograde perfusion. By using a proximal segment of the right internal mammary artery as patch material, we assumed(More)