Arnaud Pommier

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Tumors affect myelopoeisis and induce the expansion of myeloid cells with immunosuppressive activity. In the MT/ret model of spontaneous metastatic melanoma, myeloid cells are the most abundant tumor infiltrating hematopoietic population and their proportion is highest in the most aggressive cutaneous metastasis. Our data suggest that the tumor(More)
In recent years, broad classes of cells derived from the mononuclear phagocytic lineage, including myeloid-derived suppressor cells 1 and tumor-associated macro-phages, 2 have been intensively investigated and found to promote the growth and metastatic dissemination of malignant cells. Conversely, the potential antineo-plastic activity of monocytic cells(More)
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