Arnaud Mommerot

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The objective of the present study was to evaluate the effects of inhaled and intravenous sildenafil on the pulmonary endothelium-dependent relaxations, the hemodynamic profile and oxygenation after cardiopulmonary bypass. Five groups of Landrace swine were compared: 1) control; 2) cardiopulmonary bypass: 90 min of normothermic cardiopulmonary bypass; 3)(More)
INTRODUCTION Evidence regarding the behavior of fibrinogen levels and the relation between fibrinogen levels and postoperative bleeding is limited in cardiac surgery under cardiopulmonary bypass (CPB). To evaluate perioperative fibrinogen levels as a predictor of postoperative bleeding in patients undergoing cardiac surgery with CPB. MATERIALS AND METHODS(More)
BACKGROUND This study was conducted to identify preoperative predictors of postoperative atrial fibrillation (POAF) after isolated coronary artery bypass grafting (CABG) by using a Bayesian analysis that included information from prior studies. METHODS We performed a prospective observational study from October 2008 to December 2013 of 1,481 patients who(More)
OBJECTIVE Whereas it is established that endothelin-1 elicits sustained deleterious effects on the cardiovascular system during cardiopulmonary bypass (CPB), presently it remains unknown whether the inhaled administration of the dual ETA and ETB antagonist tezosentan prevents the development of pulmonary endothelial dysfunction. DESIGN A prospective,(More)
OBJECTIVE : The new poloxamer 407 (LeGoo), a thermoreversible gel, previously showed efficiency in temporarily occluding coronary arteries and preserving endothelial function. However, its long-term effect on the myocardium after dissolution in bloodstream is uncertain. METHODS : Two groups of pigs (12 total) were compared after being submitted to a(More)
BACKGROUND Obesity is suggested to reduce postoperative bleeding in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) but perioperative hemostasis variations have not been studied. Therefore, we investigated the effects of severe obesity (body mass index [BMI] ≥35kg/m(2)) on chest tube output (CTO) and hemostasis in patients undergoing(More)
BACKGROUND Unfractionated heparin has been the standard anticoagulant used immediately after mechanical heart valve replacement (MHVR). The purpose of this study was to assess a postoperative anticoagulation protocol with low-molecular-weight heparin (LMWH) immediately after MHVR without the use of unfractionated heparin or anti-factor Xa monitoring. (More)
Chronic mesenteric ischemia is a rare disorder that is frequently associated with coronary artery disease. Myocardial ischemia is a leading cause of morbidity and mortality after revascularization of the splanchnic arteries. The optimal treatment of concomitant chronic mesenteric ischemia and myocardial ischemia is unknown. We report a case of this(More)