Arnaud Lazarus

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BACKGROUND The Prospective Evaluation of Pacemaker Lead Endocarditis study is a multicenter, prospective survey of the incidence and risk factors of infectious complications after implantation of pacemakers and cardioverter-defibrillators. METHODS AND RESULTS Between January 1, 2000, and December 31, 2000, 6319 consecutive recipients of implantable(More)
Multisite biventricular pacing therapy offers significant clinical improvement in some stimulated patients with electrocardiographic criteria of cardiac dyssynchrony. However, observational data increasingly suggest that patients suffering from congestive heart failure in presence of modest QRS widening may also derive benefit from cardiac resynchronization(More)
STUDY OBJECTIVE To describe the daily routine application of a new telemonitoring system in a large population of cardiac device recipients. METHODS Data transmitted daily and automatically by a remote, wireless Home Monitoring system (HM) were analyzed. The average time gained in the detection of events using HM versus standard practice and the impact of(More)
OBJECTIVES We compared the effects of triple-site versus dual-site biventricular stimulation in candidates for cardiac resynchronization therapy. BACKGROUND Conventional biventricular stimulation with a single right ventricular (RV) and a single left ventricular (LV) lead is associated with persistence of cardiac dyssynchrony in up to 30% of patients. (More)
We investigate how the configurations obtained from thewrithing of a heavy elastic rod are influenced by its intrinsic natural curvature. To this end, we perform a combination of numerics and precision model experiments on the compression or twisting of a thin rod. The ‘softness’ of these single elastic filaments stems from their slenderness (high aspect(More)
BACKGROUND Remote monitoring (RM) can remotely detect atrial tachyarrhythmias (ATAs). The benefit of RM compared to conventional follow-up in the detection and management of ATA was assessed in recipients of dual-chamber pacemakers. METHODS The multicenter randomized SETAM study enrolled 595 patients in sinus rhythm with a CHA2 DS2 -VASc score ≥2, without(More)
BACKGROUND Impulse-conduction abnormalities and arrhythmias are common in myotonic dystrophy (MD). This study was performed to determine whether a correlation exists between electrophysiological (EP) testing data and clinical status, heart function, or size of the DNA abnormality (cytosine-thymine-guanine sequence repeat). METHODS AND RESULTS Eighty-three(More)
AIMS The choice of resynchronization therapy between with (CRT-D) and without (CRT-P) a defibrillator remains a contentious issue. Cause-of-death analysis among CRT-P, compared with CRT-D, patients could help evaluate the extent to which CRT-P patients would have additionally benefited from a defibrillator in a daily clinical practice. METHODS AND RESULTS(More)
Cardiac electrical stimulation as primary or adjunctive treatment of congestive heart failure is entering its second decade of existence. Initial trials of conventional DDD pacing were followed by bifocal right ventricular stimulation. The concept of multisite stimulation for haemodynamic support was introduced in 1994. 8 Various studies have already(More)