Armen Zakharyan

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BACKGROUND Recent pharmacodynamic and retrospective clinical analyses have suggested that proton pump inhibitors (PPIs) may modify the antiplatelet effects of clopidogrel bisulfate. METHODS We conducted a retrospective cohort study of persons enrolled in a multistate health insurance plan with commercial and Medicare clients to evaluate adverse clinical(More)
Objective. To study free-radical lipid oxidation, oxidative protein modification, and glutathione peroxidase and glutathione reductase activities, as well as the end product of nitric oxide, i.e., nitrite, in the mitochondrial fraction of the brain in animals during experimental cerebral edema and treatment with taurine. Materials and methods. Toxic(More)
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