Armando Guadarrama Espinoza

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In previous studies we have shown the protective value of T. cruzi excretory/secretory antigens (ESA) as well as a synthetic peptide derived from the primary sequence of a 24-kDa protein present among ESA in mice and rats challenged with a lethal dose of T. cruzi. In the present study, the 24-kDa polypeptide was produced as a fusion protein in the pGEX-2T(More)
In the version of this article initially published online, there were two errors. In the section “Three classes of monoallelic elements” in the main text, “We classified all monoallelically accessible elements (1,966 elements)” should have read “1,964 elements.” In the legend for Figure 5c, the number of elements open in ESCs should have been given as 234(More)
Trypanosoma cruzi, the causative agent of Chagas' disease, is a protozoan parasite that infects humans and other mammals in Central and Latin America. Several alterations of the immune response after infection have been described, such as severe immunosuppression of both cellular and humoral responses and massive polyclonal B- and T-cell activation,(More)
Landraces (traditional varieties) of domesticated species preserve useful genetic variation, yet they remain untapped due to the genetic linkage between the few useful alleles and hundreds of undesirable alleles. We integrated two approaches to characterize the diversity of 4,471 maize landraces. First, we mapped genomic regions controlling latitudinal and(More)
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