Recent studies in the literature have appliedphylogenetic methods based on genetic distancesto set priorities for conservation of domesticanimal breeds. While these methods may beappropriate for… (More)
Genetic parameters widely used to monitor genetic variation in conservation programmes, such as effective number of founders, founder genome equivalents and effective population size, are… (More)
Effective population size is a key parameter in evolutionary and quantitative genetics because it measures the rate of genetic drift and inbreeding. Predictive equations of effective size under a… (More)
Proceedings of the National Academy of Sciences…
1997
Theory concerning the evolution of sex and recombination and mutation load relies on information on rates and distributions of effects of deleterious mutations. Direct information on the genomic… (More)
Equations to approximate the effective size (Ne) of populations under continued selection are obtained that include the possibility of partial full-sib mating and other systems such as assortative… (More)
Sexual selection (defined as the change in genotypic or phenotypic frequencies of mated versus total population frequencies) and sexual isolation (defined as the deviation from random mating in mated… (More)
A model of mutation-selection-drift balance incorporating pleiotropic and dominance effects of new mutations on quantitative traits and fitness is investigated and used to predict the amount and… (More)
Recent mutation accumulation results from invertebrate species suggest that mild deleterious mutation is far less frequent than previously thought, implying smaller expressed mutational loads.… (More)
Computer simulations have been carried out tocompare, under realistic genetic models, twomethods proposed in the literature to retaingenetic diversity in conservation programmes.In a two-step method,… (More)
Within the context of a conservation program the management of subdivided populations implies a compromise between the control of the global genetic diversity, the avoidance of high inbreeding… (More)