Arlinda Ellison

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Major histocompatibility complex (MHC) genes encode proteins that present pathogen-derived antigens to T-cells, initiating the adaptive immune response in vertebrates. Although populations with low MHC diversity tend to be more susceptible to pathogens, some bottlenecked populations persist and even increase in numbers despite low MHC diversity. Thus, the(More)
Objective and Design: Cystic fibrosis (CF) sputum contains large numbers of neutrophils whose most abundant granule proteins are defensins. Within phagolysosomes, defensins kill microbes; however, extracellular defensins can be toxic to human cells. To begin to explore the possibility that defensins damage CF airways, this study examines the concentration(More)
OBJECTIVE In the last decade, African-American congregations have been inundated with requests to participate in health promotion activities; however, most are not equipped to effectively participate. We assessed the effect of providing congregation leaders with skills on identifying their own health needs, planning, and implementing their own(More)
Despite being probably one of the most studied topics in Evolutionary Biology, the mechanisms of maintenance of major histocompatibility complex (MHC) diversity in vertebrates remain also one of the most debated topics [1]. Ellison et al. [2] studied MHC class I diversity of a selfing Kryptolebias marmoratus population by clustering alleles in supertypes(More)
The HIV epidemic is a health crisis in rural African American communities in the Southeast United States; however, to date little attention has been paid to community-academic collaborations to address HIV in these communities. Interventions that use a community-based participatory research (CBPR) approach to address individual, social, and physical(More)
Though African-American youth in the South are at high risk for HIV infection, abstinence until marriage education continues to be the only option in some public schools. Using community-based participatory research methods, we conducted 11 focus groups with African-American adults and youth in a rural community in North Carolina with high rates of HIV(More)
BACKGROUND We explored rural African American youths' perceptions about the role of community social institutions in addressing HIV. METHODS We conducted four focus groups with African Americans aged 16 to 24 years in two rural counties in North Carolina. Groups were stratified by gender and risk status. We used a grounded theory approach to content(More)
BACKGROUND The HIV epidemic is a major public health problem in the United States, particularly among rural African American adolescents and young adults. OBJECTIVES We sought to explore young, rural African American's perspectives about key programmatic components to consider when designing youth-targeted, community- based HIV prevention interventions.(More)
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