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  • Abraham Michael Lincoff, Jean-Claude Tardif, +10 authors Diederick E Grobbee
  • Medicine
  • American heart journal
  • 1 September 2013
  • BACKGROUND Peroxisome proliferator-activated receptors (PPARs) regulate transcription of genes involved in glucose uptake, lipid metabolism, and inflammation. Aleglitazar is a potent dual PPARContinue Reading
  • Pascal Chanu, Franz Schaefer, +7 authors Nicolas Frei dit Frey
  • Medicine
  • British journal of clinical pharmacology
  • 26 November 2019
  • AIMS Methoxy polyethylene glycol-epoetin beta (continuous erythropoietin receptor activator, C.E.R.A.) is used for the treatment of anaemia in adults with chronic kidney disease (CKD). PatientsContinue Reading
    Background C.E.R.A. indicated in Chronic Kidney Disease adult patients to correct and maintain hemoglobin (Hb) levels is approved in Europe and US since 2007; pediatric development is ongoing. AContinue Reading