Arlener D Turner

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Research has shown poor performance on verbal memory tasks in patients with major depressive disorder relative to healthy controls, as well as structural abnormalities in the subcortical structures that form the limbic-cortical-striatal-pallidal-thalamic circuitry. Few studies, however, have attempted to link the impairments in learning and memory in(More)
OBJECTIVE Provide normative data for the volumetric blood flow (cc/min and cc/min/kg) in the umbilical artery. METHODS Flow was determined from an umbilical artery in 252 normal obstetrical patients from 18-40 weeks' gestation utilizing pulsed Doppler and color flow Doppler with an angle of insonation of 30-60 degrees. Simultaneous velocimetry studies(More)
OBJECTIVE To study Doppler velocimetry in fetuses with a single umbilical artery (SUA) as compared to normal. STUDY DESIGN Private and clinic patients were referred to a perinatal center: 45 with SUA and 124 randomly selected fetuses with a three-vessel cord were studied from 18 to 41 weeks' gestation. Color Doppler flow and energy were utilized to(More)
Six sheep were each given a fluoride slow-release intra-ruminal capsule which delivered 30 +/- 1.02 mg F/d. After 20 days, fluoride balance studies were carried out for four days and serum fluoride measured daily. Each sheep was then given 23.1 mg sodium borate daily via drench gun for six days, and the balance studies continued. In a separate similar(More)
A number of inhibitors of thrombin and factor Xa have been described; however, only one inhibitor of factor IXa has been reported. This compound, dansyl-Glu-Gly-Arg chloromethyl ketone (DEGER), inhibits porcine factor IXa with a second-order rate constant of 2.2 X 10(4) M-1 min-1. We now describe the synthesis and characterization of three p-amidinophenyl(More)
Three p-amidinophenyl esters have been synthesized and characterized as irreversible inhibitors of the vitamin-K dependent proteinases; factors IXa, Xa and thrombin (Turner et al. [4]).+ In the present report we describe the in vitro and in vivo effects of these agents on standard coagulation tests in vitro and in blood from animals treated with the(More)
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