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An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.

• Pranoti Mandrekar, A. Sumit Ambade, Arlene Lim, Gyongyi Szabo, Donna Catalano
• Hepatology
• 2011

UNLABELLED The importance of chemokines in alcoholic liver injury has been implicated. The role of the chemokine, monocyte chemoattractant protein-1 (MCP-1), elevated in patients with alcoholic liver… (More)

Genetics of P-element transposition into Drosophila melanogaster centric heterochromatin.

• Alexander Y. Konev, Christopher M. Yan, +5 authors Gary H. Karpen
• Genetics
• 2003

Heterochromatin is a major component of higher eukaryotic genomes, but progress in understanding the molecular structure and composition of heterochromatin has lagged behind the production of… (More)

In vivo T-cell clonal amplification at time of acute graft-versus-host disease.

• Pierre Yves Dietrich, Anne Caignard, +7 authors Frédéric Triebel
• Blood
• 1994

In a series of patients transplanted with HLA-matched allogeneic bone marrow grafts (alloBMT), we previously showed that a few T-cell receptor (TCR) V alpha and V beta gene segment transcripts were… (More)

Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction.

• Edward I. Ginns, Sally K-K Mak, +9 authors Amy B. Manning-Boğ
• Molecular genetics and metabolism
• 2014

Clinical, epidemiological and experimental studies confirm a connection between the common degenerative movement disorder Parkinson's disease (PD) that affects over 1 million individuals, and Gaucher… (More)

Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.

• A. Sumit Ambade, Donna Catalano, Arlene Lim, Pranoti Mandrekar
• Hepatology
• 2012

UNLABELLED Endotoxin-mediated proinflammatory cytokines play a significant role in the pathogenesis of acute and chronic liver diseases. Heat shock protein 90 (molecular weight, 90 kDa) (hsp90)… (More)

Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury.

• A. Sumit Ambade, Donna Catalano, Arlene Lim, Andre Kopoyan, Scott A Shaffer, Pranoti Mandrekar
• Journal of hepatology
• 2014

BACKGROUND & AIMS Heat shock protein 90 (hsp90) is an emerging therapeutic target in chronic liver diseases. Hsp90 plays an important role in liver immune cell activation; however its role in… (More)

Current status of the Plasmodium falciparum genome project.

• J. B. Dame, David E. Arnot, +22 authors Erhard Werner
• Molecular and biochemical parasitology
• 1996

The Plasmodium falciparum Genome Project is a collaborative effort by many laboratories that will provide detailed molecular information about the parasite, which may be used for developing practical… (More)

Human Binge Alcohol Intake Inhibits TLR4-MyD88 and TLR4-TRIF Responses but Not the TLR3-TRIF Pathway: HspA1A and PP1 Play Selective Regulatory Roles.

• Sujatha Muralidharan, Arlene Lim, Donna Catalano, Pranoti Mandrekar
• Journal of immunology
• 2018

Binge/moderate alcohol suppresses TLR4-MyD88 proinflammatory cytokines; however, alcohol's effects on TLR-TRIF signaling, especially after in vivo exposure in humans, are unclear. We performed a… (More)

Genomic organization of Lactococci.

• B. E. Davidson, Nancy Kordias, Nina Baseggio, Arlene Lim, Marian Dobos, Alan J. Hillier
• Developments in biological standardization
• 1995

The genus Lactococcus contains four species of which L. lactis is the most thoroughly studied. Its genome is A+T-rich and consists of a circular chromosome of 2.0 to 2.7 Mbp, a wide range of… (More)

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