Arjunan Ganesh

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Role of serotonin in olfactory recognition was tested by depleting the olfactory bulb serotonin during postnatal day (PND) 1 - 4 following administration of 5,7-dihydroxytryptamine. Significant difference in the olfactory recognition test was observed during PND5-7; control pups successfully recognized and oriented towards their mother; whereas treated pups(More)
Corticotropin-releasing factor (CRF) is a neurotransmitter in Barrington's nucleus neurons. These neurons can coregulate parasympathetic tone to the bladder (to modulate micturition) and brain noradrenergic activity (to affect arousal). To identify the role of CRF in the regulation of micturition, the effects of CRF agonists and antagonists on urodynamics(More)
Anesthetic goals for procedures involving resections close to the motor cortex include immobility, analgesia, and a level of consciousness that allows for the ability to follow motor commands. Remifentanil as a single agent is an attractive choice, particularly when ventilation is controlled. The successful use of large-dose remifentanil infusion during an(More)
Published with the written consent of the patient and her parents. No external funding or competing interests declared. 1 Fertleman CR, Ferrie CD, Aicardi J, et al. Paroxysmal extreme pain disorder (previously familial rectal pain syndrome). Neurology 2007; 69: 586–95. 2 Fertleman CR, Baker MD, Parker KA, et al. SCN9A mutations in par-oxysmal extreme pain(More)
We report a case series of five adolescents who were managed with dual simultaneous perineural infusions after orthopaedic surgery on an outpatient basis. Adolescents undergoing orthopaedic procedures involving more than one extremity or nerve distribution can be managed after operation with multiple catheters. Use of low concentrations of local anaesthetic(More)
ultrasound has changed medical practice. Ultrasonography can confirm endotracheal intubation, assess vocal cord function, detect endobronchial intubation and diagnose pneumothorax. We present a novel use of real time ultrasound to guide tracheal intubation in a series of 25 children. This new technique is called Ultrasound Guided Tracheal Intubation (UGTI).(More)
The indications for surgery on the knee in children and adolescents share some similarity to adult practice in that there are an increasing number of sports-related injuries requiring surgical repair. In addition, there are some unique age-related conditions or congenital abnormalities that may present as indications for orthopedic intervention at the level(More)
(heat, oxidative stress, and nitrogen species as triggers) or in vivo (using 31 P MRI) 6 need to be developed. " Regarding item 2: Again, the statement about possible indicators for individuals at risk for nonanesthetic MH was taken from the original context. It is very clear from the whole paragraph and the statements made immediately preceding the(More)
BACKGROUND Intrathecal morphine (ITM) provides effective analgesia after posterior spinal fusion (PSF). Although most anesthetic drugs have well-characterized effects on evoked potentials, there is little data on the effects of ITM on transcranial electric motor-evoked potentials (tceMEPs). We performed this study to assess the effects of ITM on tceMEPs in(More)
BACKGROUND The authors evaluated the efficacy of adding fentanyl to epidural bupivacaine in infants up to 6 months of age after a thoracotomy in a prospective, randomized, double-blind study. The primary outcome was the total amount of rescue doses of intravenous nalbuphine in the first 24 h after surgery. Secondary outcomes included (1) time to first(More)