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  • Aristeidis Giannakopoulos, Eleana F. Stavrou, Ioannis K. Zarkadis, Nicholas C. Zoumbos, Adrian J. Thrasher, Aglaia Athanassiadou
  • Biology, Medicine
  • Journal of molecular biology
  • 2009 (First Published: 1 April 2009)
  • The scaffold/matrix attachment regions (S/MARs) are chromosomal elements that participate in the formation of chromatin domains and have origin of replication support functions. Because of all theseContinue Reading
  • Marios Kaliakatsos, Aristeidis Giannakopoulos, +7 authors Maria Tzetis
  • Biology, Medicine
  • Journal of Human Genetics
  • 2010 (First Published: 1 November 2010)
  • Phenotypic variation in CHARGE syndrome remains unexplained. A subcategory of CHARGE patients show overlapping phenotypic characteristics with DiGeorge syndrome (thymic hypo/aplasia, hypocalcemia,Continue Reading
  • Eleana F. Stavrou, Vassileios M. Lazaris, +5 authors Aglaia Athanassiadou
  • Biology, Medicine
  • Scientific reports
  • 2017 (First Published: 1 February 2017)
  • Specific human chromosomal elements enhance the performance of episomal gene-transfer vectors. S/MAR-based episomal vector pEPI-eGFP transfects CD34+ haematopoietic cells, but only transiently. ToContinue Reading
    Episomal gene transfer for gene therapy applications is limited at present mainly because of luck of long term persistence of episomes in the nucleus of cells. However, episomal vectors may offer aContinue Reading