Ariane Nunes Rodrigues

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OBJECTIVES This study analyzed oncological and functional results of supracricoid horizontal partial laryngectomy. METHODS A retrospective study was conducted involving 20 patients with squamous cell carcinoma (SCC) of the larynx who underwent SCPL between 1996 and 2005 in Faculty of Medical Sciences of Santa Casa Hospital of Sao Paulo, Brazil. There were(More)
17026 Background: SCLC is an aggressive malignancy, but has shown high response rate to CT. Performance status (PS) has been recognized as one of the main prognostic factors in SCLC. Sudden and toxic deaths after CT were found to correlate with poor PS. There are few data about risk-benefit ratio of CT in PS 3 and 4 patients, although it has been often(More)
5033 Background: Concurrent cisplatin (C) based chemoradiotherapy (CRT) is the standard treatment for locally advanced cervical cancer (LACC). New strategies that increase the complete response (CR) rates may lead to longer progression-free(PFS) and overall survival(OS). Pre-clinical data indicates that inhibition of the epidermal growth factor receptor(More)
13081 Background: Pre-clinical data indicates that inhibition of epidermal growth factor receptor (EGFR) potentiates the effect of RT. This phase I trial aims to determine the maximal tolerated dose (MTD) of erlotinib, an oral EGFR tyrosine kinase inhibitor, when administered concurrently with standard chemoradiation (CRT) for cervical cancer. METHODS In(More)
The dynamism and intensity of the adoption of practical learning problems (PBL) provide adverse effects contrary to traditional learning approaches. The difficulty in defining clear educational objectives aligned to appropriate forms of assessment is also a recurring challenge in the management of learning environments. As a response to this state of(More)
17136 Background: Platinum-based chemotherapy (PtCT) is the standard 1st-line treatment for advanced stage NSCLC patients. Nearly all patients (pts) that respond to 1st-line CT will relapse and some of them will be candidates for 2nd-line CT. There is no consensus definition of sensitive or resistant pts to PtCT and there are conflicting results about the(More)
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