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BACKGROUND AND PURPOSE To screen for glucocerebrosidase (GBA) mutations in a Serbian Parkinson's disease (PD) population. METHODS Glucocerebrosidase exons 8-11 harbouring the most common mutations were sequenced in 360 patients with PD and 348 controls from Serbia. Haplotype analysis was performed for the N370S mutation and compared with German and(More)
Morphology has a crucial effect on productivity and the supply of substrate for cultures of filamentous fungi. However, cultivation parameters leading to the desired morphology are often chosen empirically as the mechanisms governing the processes involved are usually unknown. For coagulating microorganisms like Aspergillus niger the morphological(More)
The control of defect mediated optical absorption at a wavelength of 1550 nm via charge state manipulation is demonstrated using optical absorption measurements of indium doped Silicon-On-Insulator (SOI) rib waveguides. These measurements introduce the potential for modulation of waveguide transmission by using the local depletion and injection of(More)
In 12 of 49 patients operated on for liver injuries we performed sonographic examination of the abdomen on admission to hospital within the framework of emergency diagnostics. The most sensitive finding was the identification of the presence of intraabdominal free fluid. The liver injury itself was sonographically diagnosed in only 5 patients.(More)
Between 1978 and 1985 a total of 49 patients (20 women and 29 men, aged 31-78 years) were operated upon for liver metastases of a colorectal carcinoma. Metastasis recurrences occurred in 42 of 46 patients (91%). Three patients died in connection with the operation (6.1%). The five-year survival rate was 10.7%. Neither number, site and volume of the(More)
We demonstrate a method for the efficient modulation of optical wavelengths around 1550 nm in silicon waveguides. The amplitude of a propagating signal is mediated via control of the charge state of indium centers, rather than using free-carriers alone as in the plasma-dispersion effect. A 1×1 switch formed of an integrated p-i-n junction in an indium-doped(More)
Marginally perceptible prototypes as primes lead to slowed reactions to related category exemplars as compared to unrelated ones. This at first glance counterintuitive finding has been interpreted as evidence for a particular mechanism of lateral inhibition, namely the centre surround inhibition mechanism. We investigated the semantic surround of category(More)
The influence of internalizing and externalizing problems on children's understanding of others' emotions has mainly been investigated on basic levels of emotion comprehension. So far, studies assessing more sophisticated levels of emotion comprehension reported deficits in the ability to understand others' emotions in children with severe internalizing or(More)