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- Rayjean J Hung, James McKay, +62 authors Paul Brennan
- Nature
- 2008
Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually. To identify genetic factors that modify disease risk, we conducted a genome-wide association… (More)
- Ariana Znaor, Paul Brennan, +4 authors Paolo Boffetta
- International journal of cancer
- 2003
Oral, pharyngeal and esophageal cancers are 3 of the 5 most common cancer sites in Indian men. To assess the effect of different patterns of smoking, chewing and alcohol drinking in the development… (More)
- Stefano Bonassi, Ariana Znaor, +21 authors Michael Fenech
- Carcinogenesis
- 2007
The frequency of micronuclei (MN) in peripheral blood lymphocytes (PBL) is extensively used as a biomarker of chromosomal damage and genome stability in human populations. Much theoretical evidence… (More)
- Pagona Lagiou, Christina Georgila, +28 authors Paul Brennan
- European journal of cancer prevention : the…
- 2009
Cancers of the upper aerodigestive tract (UADT) include those of the oral cavity, pharynx (other than nasopharynx), larynx, and esophagus. Tobacco smoking and consumption of alcoholic beverages are… (More)
- Sébastien Antoni, Jacques Ferlay, Isabelle Soerjomataram, Ariana Znaor, Ahmedin Jemal, Freddie Bray
- European urology
- 2017
CONTEXT
Bladder cancer has become a common cancer globally, with an estimated 430 000 new cases diagnosed in 2012.
OBJECTIVE
We examine the most recent global bladder cancer incidence and mortality… (More)
- Ariana Znaor, Joannie Lortet-Tieulent, Mathieu Laversanne, Ahmedin Jemal, Freddie Bray
- European urology
- 2015
CONTEXT
Renal cell carcinoma (RCC) incidence rates are higher in developed countries, where up to half of the cases are discovered incidentally. Declining mortality trends have been reported in… (More)
- Mia Hashibe, James D McKay, +46 authors Paul Brennan
- Nature Genetics
- 2008
Alcohol is an important risk factor for upper aerodigestive cancers and is principally metabolized by alcohol dehydrogenase (ADH) enzymes. We have investigated six ADH genetic variants in over 3,800… (More)
- David Ian Conway, Darren R Brenner, +72 authors Paul Brennan
- International journal of cancer
- 2015
Low socioeconomic status has been reported to be associated with head and neck cancer risk. However, previous studies have been too small to examine the associations by cancer subsite, age, sex,… (More)
N2-ethyldeoxyguanosine as a potential biomarker for assessing effects of alcohol consumption on DNA.
- Silvia Balbo, Mia Hashibe, +14 authors Paolo Boffetta
- Cancer epidemiology, biomarkers & prevention : a…
- 2008
Head and neck cancers are causally related to alcohol consumption, but the underlying mechanisms are unclear. Ethanol is metabolized to acetaldehyde, an experimental carcinogen. Quantitation of the… (More)
- Stefano Bonassi, Hannu Norppa, +13 authors Paolo Boffetta
- Carcinogenesis
- 2008
Mechanistic evidence linking chromosomal aberration (CA) to early stages of cancer has been recently supported by the results of epidemiological studies that associated CA frequency in peripheral… (More)