Ari D. Brooks

Learn More
BACKGROUND Castleman's disease (CD), or angiofollicular lymph node hyperplasia, creates both diagnostic and therapeutic dilemmas for most physicians. For patients with this rare and poorly understood disease, the optimal therapy is unknown. The authors report their experience during the years 1986-1997 with this uncommon clinicopathologic entity. METHODS(More)
The majority of HIV-infected individuals fail to produce protective antibodies and have diminished responses to new immunizations. We report here that even though there is an expansion of follicular helper T (TFH) cells in HIV-infected individuals, the cells are unable to provide adequate B cell help. We found a higher frequency of programmed cell death(More)
STUDY OBJECTIVES To examine the incidence and clinical significance of prolonged air leak (PAL) in patients undergoing radical upper lobectomy and to determine potential risk factors for PAL in this group of patients. DESIGN Retrospective review of a prospective database. SETTING Experience of one thoracic surgeon at a tertiary care cancer center. (More)
Oxidative stress leads to membrane lipid peroxidation, which yields products causing variable degrees of detrimental oxidative modifications in cells. Reactive oxygen species (ROS) are the key regulators in this process and induce lipid peroxidation in Escherichia coli. Application of nonthermal (cold) plasma is increasingly used for inactivation of surface(More)
OBJECTIVE The purpose of the study was to determine whether early postoperative enteral feeding with an immune-enhancing formula (IEF) decreases morbidity, mortality, and length of hospital stay in patients with upper gastrointestinal (GI) cancer. SUMMARY BACKGROUND DATA Early enteral feeding with an IEF has been associated with improved outcome in trauma(More)
Closed suction drains after pancreaticoduodenectomy are theoretically used to drain potential collections and anastomotic leaks. It is unknown whether such drains are effective, harmful, or affect the outcome after this operation. Eighty-nine consecutive patients underwent pancreaticoduodenectomy for presumed periampullary malignancy and were(More)
Direct and indirect influence onmicroorganisms of non-thermal atmospheric-pressure DBD in air is compared in terms of bacterial inactivation rates. It is demonstrated that direct influence of the plasma, where charged particles contact bacteria directly, produces inactivation much faster than the indirect treatment, where plasma afterglow is delivered to(More)
Initiation of apoptosis, or programmed cell death, is an important issue in cancer treatment as cancer cells frequently have acquired the ability to block apoptosis and thus are more resistant to chemotherapeutic drugs. Targeted and G. Fridman (&) School of Biomedical Engineering, Science, and Health Systems, Drexel University, 3141 Chestnut Street,(More)
Lexical chaining is a technique for identifying semantically-related <i>terms</i> in text. We propose <i>concept chaining</i> to link semantically-related <i>concepts</i> within biomedical text together. The resulting concept chains are then used to identify candidate sentences useful for extraction. The extracted sentences are used to produce a summary of(More)