Arham Shabbir

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Rhus coriaria Linn. (Anacardiacea), commonly known as sumac, has been used as a spice, condiment, appetizer, and as a souring agent for centuries. A broad range of nutritionally and medicinally significant phytochemical components have been identified from various parts of sumac such as tannins, flavonoids, anthocyanins, organic acids, flavones, proteins,(More)
Benzothiazine and pyrazole derivatives possess anti-inflammatory properties. Previously, synergism of both heterocyclic moieties into a single nucleus has shown to produce biologically active N'-arylmethylidene-2-(3,4-dimethyl-5,5-dioxidopyrazolo(4,3-c)(1,2)benzothiazin-2(4H)yl)acetohydrazides) compound. Present study investigates the anti-arthritic effect(More)
CONTEXT Ginger has been used commonly in the traditional system of medicine for the treatment of respiratory disorders. OBJECTIVE The present study investigates the immunosuppressive activity of ginger by using the mouse model of ovalbumin-induced allergic asthma. MATERIALS AND METHODS Treatment with ethanol extract (500 mg/kg) and aqueous extract (720(More)
BACKGROUND Natural products are considered as an essential source for the search of new drugs. Pistacia integerrima galls (PI) have been used for the treatment of asthma and cough in traditional system of medicine. AIM/HYPOTHESIS Current study investigates the immunomodulatory and anti-inflammatory activities of P. integerrima in mouse model of(More)
ETHNOPHARMACOLOGICAL RELEVANCE Astragalus membranaceus either alone or in combination with Angelica sinensis has been used traditionally for kidney disease in East Asia and China for thousands of years. Previous studies using in vivo animal models have shown the benefits of these medicinal herbs in kidney diseases that involve oxidative stress. However, the(More)
Oxidative stress plays a key role in the pathogenesis of various diseases. Antioxidants protect the cells and tissues from oxidative stress by scavenging free radicals and reactive oxygen species. These antioxidants may be endogenous or exogenous. Plants are considered as potential and powerful exogenous source of antioxidants. Astragalus species (spp.),(More)
ETHNOPHARMACOLOGICAL RELEVANCE Various medicinal plants have protective properties against the toxicities of the venom of cobra snake (Naja species). They may be used as local first aid for the treatment of snakebite victims, and can significantly inhibit lethality, cardio-, neuro-, nephro- and myotoxicity, hemorrhage, and respiratory paralysis induced by(More)
BACKGROUND According to a pathfinder survey conducted by World Health Organization, dental caries is the single most common chronic childhood disease in Pakistan. The update information regarding dental health of school children of Sargodha district is required to plan community caries prevention programs and for better understanding of existing situation,(More)
The anti-inflammatory activities of benzothiazine and pyrazole derivatives are well documented. A series of novel N′-arylmethylidene-2-(3,4-dimethyl-5,5-dioxidopyrazolo(4,3 c)(1,2) benzothiazin-2(4H)yl) acetohydrazide compounds were previously synthesized by combining benzothiazine and pyrazole moieties into a single nucleus. The current study investigates(More)
BACKGROUND Natural products have a prime importance as an essential source for new drug discovery. Carica papaya leaves (CPL) have been used to treat inflammation in traditional system of medicine. AIM/HYPOTHESIS Current study evaluates the anti-inflammatory and immunomodulatory effects of CPL extract using mouse model of ovalbumin- (OVA) induced allergic(More)