Archana Vidya Boopathy

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Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most common cause of cardiac dysfunction due to local cell death and a temporally regulated inflammatory response. Current therapeutics are limited by delivery vehicles that do not address spatial and temporal aspects of healing. The aim of this study was to engineer(More)
Administration of bone marrow-derived mesenchymal stem cells (MSCs) after myocardial infarction (MI) results in modest functional improvements. However; the effect of microenvironment changes after MI, such as elevated levels of oxidative stress on cardiogenic gene expression of MSCs, remains unclear. MSCs were isolated from the bone marrow of adult rats(More)
UNLABELLED Children with congenital heart diseases have increased morbidity and mortality, despite various surgical treatments, therefore warranting better treatment strategies. Here we investigate the role of age of human pediatric cardiac progenitor cells (hCPCs) on ventricular remodeling in a model of juvenile heart failure. hCPCs isolated from children(More)
Gratefully dedicated to my parents For giving me wings to pursue my dreams and roots to come back to iv ACKNOWLEDGEMENTS Most of all, I want to thank to my advisor and mentor, Dr. Michael Davis, for his immense support in making this work possible. For giving me the opportunity to pursue graduate school under his guidance based on a phone interview many(More)
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