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Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria
Natural killer T (NKT) cells recognize glycosphingolipids presented by CD1d molecules and have been linked to defense against microbial infections. Previously defined foreign glycosphingolipidsExpand
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A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells.
CD1d presentation of alpha-galactosyl ceramides to natural killer T cells has been a focal point of the study of regulatory T cells. KRN7000, an alpha-galactosyl ceramide originally generated fromExpand
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Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells
Microsomal triglyceride transfer protein (MTP), an endoplasmic reticulum (ER) chaperone that loads lipids onto apolipoprotein B, also regulates CD1d presentation of glycolipid antigens in the liverExpand
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Invariant NKT cells recognize glycolipids from pathogenic Gram-positive bacteria
Natural killer T cells (NKT cells) recognize glycolipid antigens presented by CD1d. These cells express an evolutionarily conserved, invariant T cell antigen receptor (TCR), but the forces that driveExpand
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The Adaptor Protein AP-3 Is Required for CD1d-Mediated Antigen Presentation of Glycosphingolipids and Development of Vα14i NKT Cells
Relatively little is known about the pathway leading to the presentation of glycolipids by CD1 molecules. Here we show that the adaptor protein complex 3 (AP-3) is required for the efficientExpand
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Invariant NKT cells are required for airway inflammation induced by environmental antigens
House dust contains antigens capable of activating mouse and human iNKT cells, contributing to allergen-induced airway inflammation.
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The sum of a linear and a linear fractional transportation problem with restricted and enhanced flow
Abstract In this paper, a transportation problem with an objective function as the sum of a linear and linear fractional function is considered. We present an algorithm to solve the aboveExpand
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Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.
Mouse natural killer T (NKT) cells expressing an invariant T cell antigen receptor (TCR) recognize glycosphingolipids (GSLs) from Sphingomonas bacteria. The synthetic antigens previously tested,Expand
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In the present paper a fixed charge bi-criterion quadratic transportation problem with enhanced flow is studied. An algorithm to find an efficient cost-time trade off pairs in a fixed chargeExpand
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Involvement of Secretory and Endosomal Compartments in Presentation of an Exogenous Self-Glycolipid to Type II NKT Cells1
Natural Killer T (NKT) cells recognize both self and foreign lipid Ags presented by CD1 molecules. Although presentation of the marine sponge-derived lipid αGalCer to type I NKT cells has been wellExpand
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