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Common carotid intima-media thickness was measured by B-mode ultrasound imaging in 46 children (mean age, 7.4 years) with serum cholesterol > or = 6.4 mmol/L (mean, 8.25 mmol/L) and in 48 children (mean age, 6.4 years) with serum cholesterol < 6.4 mmol/L (mean, 4.60 mmol/L). Maximum thickness was significantly higher in hypercholesterolemic children than(More)
BACKGROUND AND PURPOSE Studies on cardiovascular disease have preferentially involved men because of the lower frequency of the disease in preelderly women. The aim of this analysis was to examine, with the use of a standardized ultrasound protocol, a cohort of women to differentiate early atherosclerotic lesions in different carotid segments in relation to(More)
O besity in childhood increases the risk of atherosclerotic disease and death in adulthood (1). A dramatic increase in overweight among children and adolescents during the past 2 decades has been documented (2). Moreover, overweight children and adolescents have an increased risk of adult obesity (3). A clustering of factors typical of the insulin(More)
BACKGROUND AND PURPOSE The association between obesity and atherosclerotic disease is controversial. In the present analysis, we evaluated whether common carotid intima-media thickness (IMT) and area, 2 markers of preclinical atherosclerosis, were increased in obese subjects. METHODS More than 5000 middle-aged women (n=5062; age, 30 to 69 years) living in(More)
BACKGROUND AND PURPOSE Homocystinuria due to cystathionine beta-synthase deficiency and familial hypercholesterolemia are inherited disorders of metabolism that are associated with premature development of cardiovascular disease. This study addresses the possibility that different patterns of carotid wall damage and cerebral blood flow hemodynamics are(More)
The aim of this study was to evaluate the influence of traditional and nontraditional (oxidation markers) cardiovascular risk factors on the degree of adaptive response of the carotid wall to atherosclerotic disease, a process known as arterial enlargement. Five thousand sixty-two clinically healthy, middle-aged women living in the area of Naples(More)
Let G be a non-compact, real semisimple Lie group. We consider maximal complexifications of G which are adapted to a distinguished one-parameter family of naturally reductive, left-invariant metrics. In the case of G = SL 2 (R) their realization as equivariant Riemann domains over G C = SL 2 (C) is carried out and their complex-geometric properties are(More)
Let G/K be a non-compact, rank-one, Riemannian symmetric space and let G C be the universal complexification of G. We prove that a holomorphically separable, G-equivariant, Riemann domain over G C /K C is necessarily univalent, provided that G is not a covering of SL(2, R). As a consequence of the above statement one obtains a univalence result for(More)