Araceli Muñoz-Garach

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Metabolomic studies aimed to dissect the connection between the development of type 2 diabetes and obesity are still scarce. In the present study, fasting serum from sixty-four adult individuals classified into four sex-matched groups by their BMI [non-obese versus morbid obese] and the increased risk of developing diabetes [prediabetic insulin resistant(More)
OBJECTIVE Hyperglycemia may increase mortality in patients who receive total parenteral nutrition (TPN). However, this has not been well studied in noncritically ill patients (i.e., patients in the nonintensive care unit setting). The aim of this study was to determine whether mean blood glucose level during TPN infusion is associated with increased(More)
BACKGROUND Malnutrition in hospitalized patients is associated with an increased risk of death, in both the short and the long term. AIMS The purpose of this study was to determine which nutrition-related risk index predicts long-term mortality better (three years) in patients who receive total parenteral nutrition (TPN). METHODS This prospective,(More)
CONTEXT The relationship between 25-hydroxyvitamin D [25(OH)D] and obesity and type 2 diabetes is not completely understood. Vitamin D receptor (VDR) expression in adipose tissue (AT) is related to obesity and might be regulated by 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. OBJECTIVE To analyze serum 25(OH)D and VDR gene expression in AT according to body(More)
The relationship between obesity and other metabolic diseases have been deeply studied. However, there are clinical inconsistencies, exceptions to the paradigm of "more fat means more metabolic disease", and the subjects in this condition are referred to as metabolically healthy obese (MHO).They have long-standing obesity and morbid obesity but can be(More)
Myostatin and irisin are two myokines related to energy metabolism, acting on skeletal muscle and recently suggested on adipose tissue in mice. However, the exact role of these myokines in humans has not been fully established. Our aim was to evaluate the relationship between serum levels of myostatin and irisin in type 2 diabetes mellitus patients and(More)
GABRIEL OLVEIRA, PHD MAR IA JOSÉ TAPIA, MD JULIA OCÓN, PHD CARMEN CABREJAS-GÓMEZ, MD MAR IA D. BALLESTEROS-POMAR, PHD ALFONSO VIDAL-CASARIEGO, MD CARMEN ARRAIZA-IRIGOYEN, MD JOSEFINA OLIVARES, MD MARIA DEL CARMEN CONDE-GARC IA, PHD ALVARO GARC IA-MANZANARES, MD FRANCISCO BOTELLA-ROMERO, PHD ROSA P. QU ILEZ-TOBOSO, MD LUCIO CABRERIZO, PHD PILAR MATIA, MD(More)
The importance of metabolic syndrome (MetS) lies in its associated risk of cardiovascular disease and type 2 diabetes, as well as other harmful conditions such as nonalcoholic fatty liver disease. In this report, the available scientific evidence on the associations between lifestyle changes and MetS and its components is reviewed to derive recommendations(More)
OBJECTIVE Hypoglycemia is a common problem among hospitalized patients. Treatment of hyperglycemia with insulin is potentially associated with an increased risk for hypoglycemia. The aim of this study was to determine the prevalence and predictors of hypoglycemia (capillary blood glucose <70 mg/dL) in hospitalized patients receiving total parenteral(More)