Arabinda Saha

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Sensitive and selective analytical method is required for the estimation of ramipril in human plasma as ramipril has been reported to have high intra-subject variability and phase II inactive metabolite (ramipril acyl glucuronide) back-converted to ramipril in an in vitro system. If this back conversion is not restricted, it could lead to pseudo estimation(More)
A bioanalytical method was developed and validated to estimate donepezil, 6-desmethyl donepezil and 5-desmethyl donepezil simultaneously in human plasma using galantamine as an internal standard (IS). The chromatographic separation was achieved on a reverse-phase XTerra RP (150 × 4.6 mm, 5 µm) column without affecting recovery (mean recovery > 60% with CV <(More)
A 36-year-old, previously healthy, parous woman was admitted as a gynaecological emergency with an 8-day history of dull and constant pain in the left lower abdomen. The onset was insidious. The pain was associated with constipation, radiated to the small of the back and was aggravated by movement. The woman complained of loss of appetite and there was no(More)
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