Arabinda Chaudhuri

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Protein factors involved in lipofection pathways remain elusive. Using avidin-biotin affinity chromatography and mass finger printing analysis technique, herein we report the identification of a 70 kDa size protein (bovine serum albumin precursor, BSAP) which binds strongly with lipoplexes and may play role in lipofection pathway. Using multiple cultured(More)
Cell division cycle homologue 20 (CDC20), a key cell cycle regulator required for the completion of mitosis in organisms from yeast to human, is highly expressed in several carcinomas. Recent studies have shown that specific knockdown of CDC20 expression is capable of significantly inhibiting the growth of human pancreatic carcinoma cells. However,(More)
Agents that safely and efficiently deliver nucleic acids into the cells are critical to successful gene therapy. Cationic and amphiphilic nature of the lipofectin molecules allow stable formation of complexes with DNA and also efficient delivery DNA into cells. To a large extent the cationic lipids that are in vogue are synthesized using glycerol as the(More)
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