Learn More
OBJECTIVE To determine the effectiveness of interventions designed to prevent and treat obesity, and maintain weight loss. DESIGN A systematic review of randomised controlled trials. SUBJECTS Overweight and obese adults and children. MEASUREMENTS Post-intervention changes in weight, fat content and fat distribution, measured relative to baseline. (More)
BACKGROUND Palliative radiotherapy (RT) to the chest is often used in patients with lung cancer, but RT regimens are more often based on tradition than research results. OBJECTIVES To discover the most effective and least toxic regimens of palliative RT, and whether higher doses increase survival. SEARCH STRATEGY Electronic databases, reference lists,(More)
OBJECTIVE To examine the research evidence for the health consequences of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure. DESIGN A systematic review of published research, studies being identified by searching Medline (1966-96), Embase (1974-96), and CINAHL (Cumulative Index to Nursing and Allied Health Literature)(More)
This paper is an edited version of EVective Health Care volume 6 number 1, 1 which summarises information originally derived from systematic reviews undertaken to inform national clinical practice guidelines, 2 3 supplemented and re-analysed by the NHS Centre for Reviews and Dissemination. Renal complications of type 2 diabetes Raised blood glucose levels(More)
Non-small-cell lung cancer is one of the most common malignant tumors worldwide. The majority of patients are not treatable with curative intent because of the extent of disease or patient comorbidity. Radiotherapy to the primary intrathoracic tumor is used with the aim of palliating troublesome local symptoms in approximately 25% of patients. The(More)