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  • Robert Kleemann, Aphrodite Kapurniotu, +6 authors Jürgen Bernhagen
  • Chemistry, Medicine
  • Journal of molecular biology
  • 1998 (First Published: 1 July 1998)
  • The molecular mechanism of action of macrophage migration inhibitory factor (MIF), a cytokine with a critical role in the immune and inflammatory response, has not yet been identified. Here we reportContinue Reading
  • Hongqi Lue, Aphrodite Kapurniotu, +6 authors Jürgen Bernhagen
  • Biology, Medicine
  • Cellular signalling
  • 2006 (First Published: 1 May 2006)
  • Macrophage migration inhibitory factor (MIF) is a 12.5 kD polypeptide that serves as a critical regulator of cell functions such as gene expression, proliferation or apoptosis. However, the signalContinue Reading
  • Li‐Mei Yan, Marianna Tatarek‐Nossol, Aleksandra Velkova, Athanasios Kazantzis, Aphrodite Kapurniotu
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2006 (First Published: 14 February 2006)
  • Protein aggregation into cytotoxic oligomers and fibrils in vivo is linked to cell degeneration and the pathogenesis of >25 uncurable diseases, whereas the high aggregation propensity andContinue Reading
  • Aphrodite Kapurniotu, Anke Schmauder, Konstantinos Tenidis
  • Chemistry, Medicine
  • Journal of molecular biology
  • 2002
  • Pancreatic amyloid is formed by the aggregation of the 37-residue islet amyloid polypeptide (IAPP) in type II diabetes patients and is cytotoxic. Pancreatic amyloid deposits are found in more than 95Continue Reading
  • Christian David Weber, Sandra Kraemer, +5 authors Jürgen Bernhagen
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2008 (First Published: 21 October 2008)
  • We have recently identified the archaic cytokine macrophage migration inhibitory factor (MIF) as a non-canonical ligand of the CXC chemokine receptors CXCR2 and CXCR4 in inflammatory and atherogenicContinue Reading
  • Ruediger Blindt, Felix Vogt, +12 authors Christian Weber
  • Medicine
  • Journal of the American College of Cardiology
  • 2006 (First Published: 1 May 2006)
  • OBJECTIVES Novel stents loaded with an integrin-binding cyclic Arg-Gly-Asp peptide (cRGD) were analyzed for their potential to limit coronary neointima formation and to accelerate endothelializationContinue Reading