Aparna Palit

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UNLABELLED BACKGROUND; Chikungunya fever is an Aedes mosquito-borne Arbo viral illness with significant morbidity. METHODS In a recent outbreak of the disease in south India, the dermatologic manifestations of 145 patients attending a tertiary care hospital were recorded. RESULTS All age groups were affected, including newborns. Some of the cutaneous(More)
BACKGROUND Primary cutaneous nocardiosis is an uncommon entity. It usually occurs among immunocompetent but occupationally predisposed individuals. AIM To study clinical profile of patients with primary cutaneous nocardiosis in a tertiary care hospital and to review the literature. METHODS The records of 10 cases of primary cutaneous nocardiosis were(More)
BACKGROUND The metabolic complications and pathologic changes that occur in diabetes mellitus (DM) influence the occurrence of various dermatoses. AIM To study the impact of control of diabetes on the pattern of cutaneous disorders. MATERIALS AND METHODS A cross-sectional descriptive study of patients attending diabetic clinic in a tertiary care(More)
A girl presented with severely stunted growth, photosensitivity, and a characteristic facies. Cytogenetic studies were suggestive of Bloom syndrome. This disorder has not been previously documented in the literature in an Indian child. Minor variations in characteristics in this patient have been highlighted. Cytogenetically, she was found to be a low(More)
Childhood vitiligo is often encountered in dermatological practice. When present in infancy or early childhood, various nevoid and hereditary disorders are to be differentiated. In many cases, familial aggregation of the disease is seen and other autoimmune disorders may be associated. Segmental presentation is more common, and limited body surface area(More)
Systemic sclerosis (SS) and dermatomyositis (DM) are both multisystem disorders and share some common clinical features. We report here an 11 year-old girl whose disease showed a changing clinical pattern from juvenile systemic sclerosis (JSS) to slowly progressing juvenile dermatomyositis (JDM) and had associated generalized morphea. Serological studies(More)
Use of immunohistochemical technique is increasing in diagnosing various diseases. In many situations it may not be possible to differentiate entities with overlapping clinical and histopathological features. Immunostaining of cellular antigens is immensely helpful in such cases. Immunohistochemistry (IHC) has also been in use for targeted cancer therapy.(More)
Vasculitides is a group of disorders characterized by inflammation of vessel walls. The unique feature of this group is multi-organ involvement. Because of the rich vasculature, the skin is prone to be frequently affected in vasculitis. Cutaneous involvement in vasculitides may be primary or reflector of a fatal systemic disease or evidence of association(More)
Kindler syndrome (KS) is a rare inherited skin disorder with blistering and poikiloderma as its main clinical features. It is caused by loss-of-function mutations in the C20orf42 (KIND1) gene which encodes kindlin-1, an actin cytoskeleton-focal contact-associated protein which is predominantly expressed in keratinocytes. We investigated the molecular basis(More)
rate in terms of the amount of sweat produced and the virtual absence of failures. On the first day of life the average level of sweat sodium was decidedly higher than on the second and subsequent days, with an appreciable number of day 1 results exceeding the level of 70 mEq/1., generally accepted as the upper limit of normal. In one case the level was as(More)