Family members incur substantial financial costs during the course of caring for an individual with Alzheimer's disease. Much of this cost is associated with time spent in caregiving tasks, including supervision and communication with the patient, and assisting with activities of daily living. We have previously reported on the cross sectional reliability… (More)
OBJECTIVE We sought to compare the characteristics of patients presenting with chronic fatigue (CF) and related syndromes in eight international centres and to subclassify these subjects based on symptom profiles. The validity of the subclasses was then tested against clinical data. METHOD Subjects with a clinical diagnosis of CF completed a 119-item… (More)
Factor analysis of cognitive scores from 150 patients with Alzheimer's disease yielded two orthogonal factors: one (Factor 1) loading high on spontaneous speech, repetition, comprehension, reading, writing, digit span, and left/right discrimination; the other (Factor 2) loading high on long-term memory, orientation, object naming, and abstraction.… (More)
Seventy-one incarcerated juvenile offenders were diagnosed according to DSM-III and assessed for suicidal behavior. Subjects diagnosed as having major affective disorders or borderline personality disorders showed the highest degree of suicidal tendency and had made the most serious attempts.
We related reported physical symptoms, cognitive appraisals (e.g., negative style of thinking), and coping strategies (e.g., denial/disengagement strategies) with illness burden across several functional domains separately in subsets of chronic fatigue syndrome (CFS) patients with (n = 26) and without (n = 39) concurrently diagnosed major depressive… (More)
Chronic fatigue syndrome (CFS) includes many symptoms of major depression. For this reason, many antidepressants have been used to treat the symptoms of this disorder. Among the more recently released antidepressants are fluoxetine and bupropion. In this open study, nine CFS patients who either could not tolerate or did not respond to fluoxetine showed… (More)