Anurag Chandra

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Consider the problem of estimating the small probability that the maximum of a random walk exceeds a large threshold, when the process has a negative drift and the underlying random variables may have heavy tailed distributions. We consider one class of such problems that has applications in estimating the ruin probability associated with insurance claim(More)
PURPOSE To investigate dosimetric improvements with respect to tumor-dose conformity and normal tissue sparing using intensity-modulated radiotherapy (IMRT) compared with three-dimensional conformal radiotherapy (3D-CRT) for advanced-stage non-small-cell lung cancer (NSCLC). METHODS AND MATERIALS Forty-one patients with Stage III-IV and recurrent NSCLC(More)
PURPOSE Traditionally, portal images have been used for verification of patient setup. More recently, direct prostate localization using ultrasound imaging has become available. The aim of this study was to use both modalities to measure daily setup error and prostate organ motion and their respective contributions to the overall uncertainty of prostate(More)
PURPOSE Although the interfraction motion of the prostate has been previously studied through the use of fiducial markers, CT scans, and ultrasound-based systems, intrafraction motion is not well documented. In this report, the B-mode, Acquisition, and Targeting (BAT) ultrasound system was used to measure intrafraction prostate motion during 200(More)
BACKGROUND AND PURPOSE To evaluate the feasibility whether intensity-modulated radiotherapy (IMRT) can be used to reduce doses to normal lung than three-dimensional conformal radiotherapy (3 DCRT) in treating distal esophageal malignancies. PATIENTS AND METHODS Ten patient cases with cancer of the distal esophagus were selected for a retrospective(More)
PURPOSE The NOMOS (Sewickley, PA) B-mode Acquisition and Targeting System (BAT) ultrasound system provides a rapid means of correcting for interfraction prostate positional variation. In this investigation, we report our experience on the clinical issues relevant to the daily use of the BAT system and the analysis of combined setup error and organ motion(More)
BACKGROUND Our objective was to evaluate and review the current literature on the treatment of non-small cell lung cancer (NSCLC) in the elderly. METHODS We selected recent peer-reviewed articles addressing ageing, cancer treatment in the elderly, and lung cancer treatment in the elderly. We defined elderly as over the age of 70. RESULTS The population(More)
We propose a dynamic handoff algorithm that, as compared to the static algorithm, yields reduced number of unnecessary handoffs while maintaining the Quality of Service constraints in a cellular mobile system. The fraction of unnecessary handoffs in the dynamic algorithm is found to be 25% to 30% lower than that in static algorithm. The proposed scheme(More)
Chemoradiation after surgery for locally advanced gastric cancer improves overall and relapse-free survival compared with observation. However, locoregional recurrences remain high. Accordingly, we instituted this pilot/feasibility study, including intraperitoneal 5-fluoro-2′-deoxyuridine (IP FUDR) as part of the treatment. Gastric/gastroesophageal junction(More)
Introduction Thymomas are the most common primary anterior mediastinal tumor and account for 15% to 20% of all mediastinal masses.(1, 3, 4) Although the majority of thymomas appear histologically benign, some may behave like invasive epithelial malignancies, invading local structures or metastasizing to distant organs.(2) However, extrathoracic direct(More)