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PURPOSE To investigate dosimetric improvements with respect to tumor-dose conformity and normal tissue sparing using intensity-modulated radiotherapy (IMRT) compared with three-dimensional conformal radiotherapy (3D-CRT) for advanced-stage non-small-cell lung cancer (NSCLC). METHODS AND MATERIALS Forty-one patients with Stage III-IV and recurrent NSCLC(More)
BACKGROUND AND PURPOSE To evaluate the feasibility whether intensity-modulated radiotherapy (IMRT) can be used to reduce doses to normal lung than three-dimensional conformal radiotherapy (3 DCRT) in treating distal esophageal malignancies. PATIENTS AND METHODS Ten patient cases with cancer of the distal esophagus were selected for a retrospective(More)
PURPOSE Although the interfraction motion of the prostate has been previously studied through the use of fiducial markers, CT scans, and ultrasound-based systems, intrafraction motion is not well documented. In this report, the B-mode, Acquisition, and Targeting (BAT) ultrasound system was used to measure intrafraction prostate motion during 200(More)
PURPOSE The NOMOS (Sewickley, PA) B-mode Acquisition and Targeting System (BAT) ultrasound system provides a rapid means of correcting for interfraction prostate positional variation. In this investigation, we report our experience on the clinical issues relevant to the daily use of the BAT system and the analysis of combined setup error and organ motion(More)
PURPOSE Traditionally, portal images have been used for verification of patient setup. More recently, direct prostate localization using ultrasound imaging has become available. The aim of this study was to use both modalities to measure daily setup error and prostate organ motion and their respective contributions to the overall uncertainty of prostate(More)
BACKGROUND Our objective was to evaluate and review the current literature on the treatment of non-small cell lung cancer (NSCLC) in the elderly. METHODS We selected recent peer-reviewed articles addressing ageing, cancer treatment in the elderly, and lung cancer treatment in the elderly. We defined elderly as over the age of 70. RESULTS The population(More)
Consider the problem of estimating the small probability that the maximum of a random walk exceeds a large threshold, when the process has a negative drift and the underlying random variables may have heavy tailed distributions. We consider one class of such problems that has applications in estimating the ruin probability associated with insurance claim(More)
Chemoradiation after surgery for locally advanced gastric cancer improves overall and relapse-free survival compared with observation. However, locoregional recurrences remain high. Accordingly, we instituted this pilot/feasibility study, including intraperitoneal 5-fluoro-2′-deoxyuridine (IP FUDR) as part of the treatment. Gastric/gastroesophageal junction(More)
This paper is a progress report on our study of parallel algorithms to search a binary tree for nodes possessing a hereditary property. This problem was abstracted from a specific problem of this type having to do with the chromatic number of Steinhaus graphs. The algorithms discussed have been implemented and tested on this application using MPI. The(More)
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