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OBJECTIVE To determine the effect of IV methylprednisolone (IVMP) on brain fraction volume (BFV), contrast-enhancing (CE) lesions, and white matter lesion load (WMLL) in patients with relapsing-remitting MS treated for acute exacerbations. BACKGROUND MRI metrics of MS disease activity are being used as outcome measures in early phase treatment trials,(More)
Thyrotoxic periodic paralysis (TPP) is characterized by recurrent episodes of muscle weakness and hypokalemia associated with thyroid hyperactivity. Reported predominantly among individuals of Asian descent, TPP is a rare manifestation of hyperthyroidism in western populations. We describe a typical case of TPP in a 33-year-old portuguese male, who(More)
  • Madras B Yegnanarayana, Hema Murthy, Sundar, J Y S R K Kishore, A B Rao, M Shajith +1 other
  • 1999
i ACKNOWLEDGEMENTS I like to express my sincere gratitude to Prof. B. Yegnanarayana, for having introduced me to the interesting elds of speech and neural networks. I am extremely grateful to him for the valuable guidance and encouragement he has provided throughout the course of my work. I am really fortunate to work under his guidance. I was greatly(More)
We present an algorithm that, with high probability, generates a random spanning tree from an edge-weighted undirected graph in O(n 5/3 m 1/3) time 1. The tree is sampled from a distribution where the probability of each tree is proportional to the product of its edge weights. This improves upon the previous best algorithm due to Colbourn et al. that runs(More)
This study was undertaken to assess speech discrimination under binaural listening with background noise in hearing-impaired subjects. Subjects (58 sensori-neural, 23 conductive, and 19 mixed) were administered an indigenous version of W-22 PB words under: Condition I--Quiet--chamber noise below 28 dB with speech at 60 dB; and at a constant signal-to-noise(More)
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