Anuj K. Sharma

Jungsu Kim1
Nicholas J. Hawco1
1Jungsu Kim
1Nicholas J. Hawco
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  • Marc S. Schwartz, Joseph L. Benci, Devarshi S. Selote, Anuj K. Sharma, Andy G. Y. Chen, Hope Dang +2 others
  • 2010
BACKGROUND Developing methods for protecting organisms in metal-polluted environments is contingent upon our understanding of cellular detoxification mechanisms. In this regard, half-molecule ATP-binding cassette (ABC) transporters of the HMT-1 subfamily are required for cadmium (Cd) detoxification. HMTs have conserved structural architecture that(More)
Multifunctional metal chelators that can modulate the amyloid β (Aβ) peptide aggregation and its interaction with metal ions such as copper and zinc hold considerable promise as therapeutic agents for Alzheimer's disease (AD). However, specific rather than systemic metal chelation by these compounds is needed in order to limit any side effects. Reported(More)
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