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OBJECTIVES : The aim was to assess how the use of a commercially available hearing augmentation device affected performance on cognitive assessment scales on admission to hospital. DESIGN : This was a randomized controlled trial. SETTING : The study was conducted on all of the acute assessment wards in a department of medicine for the elderly. (More)
BACKGROUND Recruitment to randomised prevention trials is challenging, not least for intracerebral haemorrhage (ICH) associated with antithrombotic drug use. We investigated reasons for not recruiting apparently eligible patients at hospital sites that keep screening logs in the ongoing REstart or STop Antithrombotics Randomised Trial (RESTART), which seeks(More)
OBJECTIVE To investigate whether the location and extent of the CT hyperdense artery sign (HAS) at presentation affects response to IV alteplase in the randomized controlled Third International Stroke Trial (IST-3). METHODS All prerandomization and follow-up (24-48 hours) CT brain scans in IST-3 were assessed for HAS presence, location, and extent by(More)
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