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Non-palpable breast lesions are diagnosed frequently posing the problem of localization and removal. When such lesions are malignant, axillary node status must be determined. We report our experience using radio-guided occult lesion localization (ROLL) for locating and removing non-palpable breast lesions together with sentinel node biopsy (SNB) to assess(More)
OBJECTIVE The purpose of our study was to assess whether in case of total removal of microcalcifications there is still residual tumor on the surgical specimen and, secondarily, to assess whether complete rather than partial excision of the imaging target with microcalcifications may result in increased diagnostic accuracy. MATERIALS AND METHODS We(More)
Breast metastatic localization from extramammary neoplasms is rare (1.7–6.6% in old autoptic series, 1.2–2% in clinical reports and 2.7% in cytological series) [1]. We describe the first case of a metastatic deposit to the breast and ovary from gastric signet-ring cell carcinoma to be reported in the literature. In March 1999, a 39-year-old woman underwent(More)
PURPOSE The aim of this study was to evaluate the diagnostic accuracy of colour-Doppler Endoscopic Ultrasonography (EUS), in the detection, loco-regional staging and assessment of vascular infiltration in pancreatic carcinoma, and to compare the results with those obtained by Computed Tomography (CT). MATERIALS AND METHODS A series of 57 patients with(More)
Several studies have shown that the thickness of tongue carcinoma is related to prognosis and to the likelihood of cervical node metastases. We investigated whether preoperative estimates of tumor thickness and volume, as determined from magnetic resonance imaging (MRI), correlated with histologic thickness and might therefore predict the presence of neck(More)
PURPOSE To determine whether low-dose tamoxifen and fenretinide have a synergistic effect on surrogate biomarkers, including circulating insulin-like growth factor I (IGF-I) and mammographic density, in premenopausal women at risk for breast cancer and to study drug safety. PATIENTS AND METHODS Premenopausal women (n = 235) were randomly assigned in a(More)
INTRODUCTION In recent decades, a steady improvement in imaging diagnostics has been observed together with a rising adherence to regular clinical breast examinations. As a result, the detection of small clinically occult (nonpalpable) lesions has progressively increased. At present in our institution some 20% of the cases are treated when nonpalpable. The(More)
1001 Background: Tamoxifen and fenretinide have been shown to reduce breast cancer incidence in pre-menopausal women at increased risk. Their combination is synergistic in reducing mammary tumor formation in animal models. METHODS We conducted a double-blind placebo controlled trial in women at high risk to determine whether there is an interaction(More)
Breast lesions defined C3 at ultrasound (US)-guided fine needle aspiration cytology (FNAC) are probably benign, but exhibit atypias. We evaluate the results of US-guided vacuum assisted breast biopsy (VABB) of these lesions. Patients diagnosed C3 by US-FNAC, submitted to US-VABB and with a minimum follow-up of 36 months or surgery were enrolled. Cost(More)
Accepted: 1 September 2003 Published online: 18 October 2003 © Springer-Verlag 2003 Sir, we observed a case of a 39-year-old woman who underwent total mastectomy and axillary lymphadenectomy with a histological diagnosis of multicentric mucinous carcinoma. A preoperative chest X-ray gave evidence to a modest enlargement of the superior outlines of(More)