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Computed tomography (CT), ultrasonography (US) and low field magnetic resonance imaging (MRI) of muscles were performed in 13 patients of a large family with two clinically separate phenotypes of muscular dystrophy. Five patients had severe proximal muscle weakness and wasting like in limb-girdle muscular dystrophy. Imaging methods showed loss of muscle(More)
A slowly progressive myopathy was discovered in a family in four successive generations. Eight patients (four female, four male) from three generations were examined and they showed muscle weakness affecting predominantly proximal, but also distal, muscles. Two patients had unequivocal findings in childhood, the others showed myopathy in their twenties or(More)
We have been following clinically and with muscle MRI for the past 3-decades a Finnish family with two patients with distal muscular dystrophy. Previously we demonstrated the cellular defect in these patients to be defective membrane repair and more recently have identified the causative gene to be anoctamin 5 (ANO5). The disorder seen in these patients is(More)
We report a 28-year-old man who suffered from episodic muscle pain, stiffness and weakness. His serum creatine kinase (CK) levels were found to be elevated. He presented with slight proximal muscle weakness and calf hypertrophy. Muscle biopsy revealed fiber size variation and tubular aggregates (TA). Muscle magnetic resonance imaging showed areas of edema.(More)
A reader module at 60 GHz for high data-rate short-range backscattering-based communications is presented. The reader consists of a CMOS-based oscillator, amplifiers, and a mixer on a low-temperature co-fired ceramic (LTCC) substrate. The filter, power splitter, and antennas are directly patterned on the LTCC. All millimeter-wave components are contained(More)
Anoctaminopathy is a new muscular dystrophy caused by mutations in the ANO5 gene. ANO5 mutations cause distal and proximal phenotypes. We report here a follow-up muscle MRI study on five patients affected by distal form of anoctaminopathy. T1 weighted scans showed subsequent involvement of gastrocnemius medialis and soleus, hip adductors, hamstrings,(More)
Improvements to an active MR tracking technique are described. Real-time position monitoring of interventional procedures can be realized by incorporating a small marker that emits an NMR signal into the tip of an interventional device, and the marker's emitted NMR signal is enhanced by use of the Overhauser phenomenon. A significant advance over prior(More)
OBJECTIVES This is a report on a retrospective muscle magnetic resonance imaging (MRI) study on 11 patients affected by Welander distal myopathy (WDM) and 22 patients with tibial muscular dystrophy (TMD) carried out in order to define the pattern and characteristics of muscle involvement. RESULTS WDM patients showed involvement of gastrocnemius, soleus,(More)
—Design and measurement results of a beam-steering integrated lens antenna at 77 GHz are presented. An 8-element LTCC aperture coupled patch antenna feed array with a switching network is used to electrically steer the main beam in H-plane. A 100-mm diameter Rexolite (ε r = 2.53) lens is simulated and tested. The eccentricity of the lens is optimized in an(More)
—This paper presents building blocks for a proposed automotive intermodulation radar for detecting and identifying vulnerable road users (VRUs). The intermodulation radar transmits at two frequencies and it has receivers both for normal reflections and for reflections from VRUs at the intermodulation frequency. A possible radar architecture is presented and(More)