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Mitochondrial dysfunction is a hallmark of almost all diseases. Acquired or inherited mutations of the mitochondrial genome DNA may give rise to mitochondrial diseases. Another class of disorders, in which mitochondrial impairments are initiated by extramitochondrial factors, includes neurodegenerative diseases and syndromes resulting from typical(More)
I read with great interest the recently published article by Balihar et al. [1] in which the authors aimed to characterize epidemiology and clinical manifestations of Clostridium difficile infection (CDI) in a Czech tertiary care center and to identify risk factors of fulminant course. They concluded that severe CDI was identified in 15.8% of patients.(More)
The purpose of study was to comparatively characterize the oxidative phosphorylation (OXPHOS) and function of respiratory chain in mitochondria in human gastric corpus mucosa undergoing transition from normal to cancer states and in human gastric cancer cell lines, MKN28 and MKN45. The tissue samples taken by endobiopsy and the cells were permeabilized by(More)
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