Antony D Rodriguez

Learn More
Electrospray ionization (ESI) generates intact gas-phase ions from analytes in solution for mass spectrometric investigations. ESI can proceed via different mechanisms. Low molecular weight analytes follow the ion evaporation model (IEM), whereas the charged residue model (CRM) applies to large globular species. A chain ejection model (CEM) has been(More)
Hydrogen/deuterium exchange (HDX) mass spectrometry (MS) is a widely used technique for probing protein structure and dynamics. Exposure to D2O induces the deuteration of backbone N-H groups via a process that involves transient excursions to partially unfolded protein conformers. The resulting mass shifts can be probed by MS, usually in combination with(More)
In computational imaging by pattern projection, a sequence of microstructured light patterns codified onto a programmable spatial light modulator is used to sample an object. The patterns are used as generalized measurement modes where the object information is expressed. In this Letter, we show that the resolution of the recovered image is only limited by(More)
Electrospray ionization (ESI) of native proteins results in a narrow distribution of low protonation states. ESI for these folded species proceeds via the charged residue mechanism. In contrast, ESI of unfolded proteins yields a wide distribution of much higher charge states. The current work develops a model that can account for this effect. Recent(More)
F0F1 ATP synthase harnesses a transmembrane electrochemical gradient for the production of ATP. When operated in reverse, this multiprotein complex catalyzes ATP hydrolysis. In bacteria, the ε subunit is involved in regulating this ATPase activity. Also, ε is essential for coupling ATP hydrolysis (or synthesis) to proton translocation. The ε subunit(More)
2014 Constant strain rate compressions along 001 > have been performed on CoO single crystals (03B5 ~ 6 x 10-5 s-1). Yield stresses and work hardening rates have been measured between 77 K and 1 400 K; CoO is very strong when compared to similar compounds. Vickers indentations have been performed on { 100 }, { 110 } and { 111 } faces around the Néel(More)
  • 1