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As part of a wider study, 242 children attending language units attached to mainstream schools were assessed on a number of formal language assessments. In addition, each child's teacher was asked to state whether, for each of four areas of language difficulty, the participant exhibited this impairment. The four areas were: articulation, phonology,(More)
Bilingual children were found to form a distinct subgroup within a large cohort of children with specific language-impairment (SLI) attending language units across England. They differed from the cohort as a whole, and from a language-matched monolingual 'control' group, on measures including language profile on entry to the unit, performance on(More)
This paper reports on the results of a large project involving 7-year-old children attending language units in England. A group of 242 children with specific language impairment (SLI) were assessed on a battery of psychometric tests. In addition, teacher interviews were carried out to ascertain teachers' opinions of the children's difficulties. Cluster(More)
ALG6-CDG (formerly named CDG-Ic) (phenotype OMIM 603147, genotype OMIM 604566), is caused by defective endoplasmic reticulum α-1,3-glucosyltransferase (E.C 2.4.1.267) in the N-glycan assembly pathway (Grünewald et al. 2000). It is the second most frequent N-glycosylation disorder after PMM2-CDG; some 37 patients have been reported with 21 different ALG6(More)
  • A Crutchley
  • 2000
Findings from a large-cohort study of children with speech and language impairments in language units attached to primary schools across England have suggested that in 11% of the cohort who were bilingual form a subgroup with distinct characteristics. In particular, bilingual children's language difficulties seemed to be more complex and possibly more(More)
We describe two unrelated male children with Gillespie syndrome, a rare genetic disorder consisting of cerebellar ataxia, partial aniridia, and psychomotor delay. One was more severely affected than the other, but neither had evidence of neuroregression. Partial aniridia was a key diagnostic marker, present at birth in both patients. Neurocognitive(More)
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