Antonios Konstantinidis

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Periodontitis is a common chronic inflammatory disease characterised by destruction of the supporting structures of the teeth (the periodontal ligament and alveolar bone). It is highly prevalent (severe periodontitis affects 10–15% of adults) and has multiple negative impacts on quality of life. Epidemiological data confirm that diabetes is a major risk(More)
BACKGROUND Various studies have examined possible correlations between a number of cytokine gene polymorphisms and periodontal disease in populations of different origins. The present study sought the correlation between four single-nucleotide polymorphisms (IL1A+3954, IL1B+4845, TNFA-308, COL1A1 Sp1), a variable number of tandem repeats polymorphism (IL1RN(More)
In this longitudinal study, five adult Down's syndrome patients with periodontitis were placed on a frequent recall visit schedule (every 6 weeks) after treatment, in order to investigate: 1) the microbiological status, both supragingivally and subgingivally, and the changes that occurred after treatment and 2) the effect of frequent professional(More)
BACKGROUND Systemically-administered tetracyclines have been used widely for treatment of periodontal diseases with little understanding of their delivery characteristics to periodontal tissues. This study was designed to measure concentrations of 3 tetracyclines in gingival crevice fluid (GCF), plasma and saliva of following systemic administration. (More)
AIM To evaluate the clinical, microbiological and immunological effects of systemic doxycycline as an adjunct to scaling and root planing (SRP) in chronic periodontitis patients with well-controlled type 2 diabetes. MATERIALS AND METHODS Sixty-six patients compliant to oral hygiene (Hygiene Index <20%) allocated to either a test (systemic doxycycline for(More)
OBJECTIVES The periodontal conditions and the subgingival microflora of children, adolescents and young adults (8-28 years old) with Down syndrome were investigated in the present cross-sectional study and compared with those of healthy individuals and subjects with cerebral palsy. MATERIAL AND METHODS Seventy Down syndrome patients, 121 age-matched(More)
OBJECTIVE To assess the prevalence of Staphylococcus aureus and methicillin resistant Staphylococcus aureus (MRSA) in plaque and tongue samples from systemically healthy subjects with periodontal health, gingivitis or chronic periodontitis. METHODS After screening 720 potentially eligible subjects, 154 systemically healthy participants were ultimately(More)
Dental prosthetic treatment of children in the primary and mixed dentition years was planned with respect to the special conditions accompanying the absence of teeth. Besides the immediate functional and esthetic benefit of prosthetic therapy, the prosthetic appliance helps to maintain the oral functional status, which is considered necessary for(More)
The aim of the present study was the evaluation of tissue response under ceramometal pontics that had smooth convex tissue surfaces and were pressing against the soft tissues of the residual ridge while the subjects were applying excellent plaque control. Fixed patial dentures were fabricated full filling the above criteria. Clinical and histologic(More)
Replacement of restorations due to secondary caries is a continuing problem in restorative dentistry. This investigation evaluated the ability of two new light-cured fluoride-containing restorative materials to inhibit caries in vitro. Class 5 cavities were prepared in buccal and lingual surfaces of 20 extracted premolars. The occlusal cavosurface margin of(More)