Antonio T Paladino

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BACKGROUND Myocardial stress CT perfusion (CTP) can detect myocardial ischemia. OBJECTIVE We evaluated the transmural perfusion ratio (TPR) of dipyridamole stress CTP to detect significant coronary stenosis (>70%) defined by quantitative invasive coronary angiography (ICA). METHODS Twenty-six patients (61.6 ± 8.0 years old; 14 males), without prior(More)
OBJECTIVE The toxicity of anti-cancer chemotherapeutic agents can be reduced by associating these compounds, such as the anti-proliferative agent paclitaxel, with a cholesterol-rich nanoemulsion (LDE) that mimics the lipid composition of low-density lipoprotein (LDL). When injected into circulation, the LDE concentrates the carried drugs in neoplastic(More)
The goal of the pixFEL project is the realization of the sensors and readout circuits for large-area imagers to be used in future X-ray Free Electron Lasers facilities. In this paper the main application requirements are highlighted and the technological solutions adopted both in the sensor and in the readout electronics are discussed. Since the final(More)
Background Hypertrophic cardiomyopathy (HCM) is a genetic disease that affects the cardiac sarcomere, resulting in myocardial hypertrophy and disarray. Affected patients have a predisposition for malignant ventricular tachyarrhythmias and, consequently, sudden cardiac death (SCD). In single center studies, late gadolinium enhancement (LGE) defined fibrosis(More)
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